NUDT12
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Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 12 -
Overview
Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and;effectors. Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide;ratios in response to changing circumstances (Abdelraheim et al., 2003 (PubMed 12790796)). -
Synonyms
NUDT12;nudix (nucleoside diphosphate linked moiety X)-type motif 12;peroxisomal NADH pyrophosphatase NUDT12;DKFZP761I172;nucleoside diphosphate linked moiety X type motif 12;0610016O18Rik;EC 3.6.1.22;Nucleoside diphosphate linked moiety X motif 12;Nudix (nucleoside diphosphate linked moiety X) type motif 12;Nudix motif 12;Nudix type motif 12;NUDT 12;OTTHUMP00000158933;OTTHUMP00000222655;nucleoside diphosphate-linked moiety X motif 12;nucleoside diphosphate linked moiety X-type motif 12
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NUDT12-1401H | Recombinant Human NUDT12, His-tagged | E.coli | Human | His | 1-377aa | |
| NUDT12-2435Z | Recombinant Zebrafish NUDT12 | Mammalian Cells | Zebrafish | His |
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| NUDT12-3124R | Recombinant Rhesus monkey NUDT12 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| NUDT12-759C | Recombinant Cynomolgus NUDT12 Protein, His-tagged | Mammalian Cells | Cynomolgus | His |
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| NUDT12-3652HCL | Recombinant Human NUDT12 293 Cell Lysate | HEK293 | Human | Non |
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| NUDT12-2943R | Recombinant Rhesus Macaque NUDT12 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| NUDT12-2943R-B | Recombinant Rhesus Macaque NUDT12 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Nudt12-4534M | Recombinant Mouse Nudt12 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| NUDT12-503C | Recombinant Cynomolgus Monkey NUDT12 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
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| NUDT12-503C-B | Recombinant Cynomolgus Monkey NUDT12 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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Involved Pathway
NUDT12 involved in several pathways and played different roles in them. We selected most pathways NUDT12 participated on our site, such as Nicotinate and nicotinamide metabolism,Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | PRDX1,MPV17,ANI_1_2390104,PEX11A,PRDX5,CRATA,NUDT7,DAO.2,AMACR,NOS2B |
| Nicotinate and nicotinamide metabolism | NT5C1A,NNT,NAPRT1,PNP,NADKD1,AOX1,AOX4,NT5C1BA,PNP6,NT5C |
Protein Function
NUDT12 has several biochemical functions, for example, NAD+ diphosphatase activity,NADH pyrophosphatase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT12 itself. We selected most functions NUDT12 had, and list some proteins which have the same functions with NUDT12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PAAF1,ERGIC2,SYT11,EIF3G,DNAJA2,RCBTB2,YY1A,MITF,C1R,TWF2 |
| NADH pyrophosphatase activity | ENPP1 |
| metal ion binding | NRXN3A,ZNF606,ZMYND17,ZNF781,TP63,ZSCAN5A,HAGH,ATP2A2A,DNAJA3,TPP1 |
Interacting Protein
NUDT12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT12 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT12.
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