NUCKS1
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Official Full Name
nuclear casein kinase and cyclin-dependent kinase substrate 1 -
Overview
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010] -
Synonyms
NUCKS1;nuclear casein kinase and cyclin-dependent kinase substrate 1;JC7;NUCKS;nuclear ubiquitous casein and cyclin-dependent kinase substrate 1;P1;potential LAG1 interactor;nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Rat
- Chicken
- Mammalian Cells
- E.coli
- HEK293
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
NUCKS1 involved in several pathways and played different roles in them. We selected most pathways NUCKS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NUCKS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NUCKS1 has several biochemical functions, for example, poly(A) RNA binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUCKS1 itself. We selected most functions NUCKS1 had, and list some proteins which have the same functions with NUCKS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | ETV2,ELF4,HOXA10,SFPI1,MZF1,ELF1,GATA3,ESR1,SOX12,ETV6 |
| poly(A) RNA binding | RPL23,TBL2,GRB2,MRPL9,PUM2,RPS17L,PHF5A,PURB,TTC6,HSD17B10 |
Interacting Protein
NUCKS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUCKS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUCKS1.
MDM2;DOCK9;AK5;MME
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