NPAS2

  • Official Full Name

    neuronal PAS domain protein 2

  • Overview

    The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain.

  • Synonyms

    NPAS2;neuronal PAS domain protein 2;neuronal PAS domain-containing protein 2;bHLHe9;MOP4;PASD4;Basic helix loop helix PAS protein MOP4;Basic-helix-loop-helix-PAS protein MOP4;Class E basic helix-loop-helix protein 9;FLJ23138;Member of PAS protein 4;Member of PAS superfamily 4;MGC71151;Neuronal PAS domain containing protein 2;Neuronal PAS2;NPAS2_HUMAN;PAS domain-containing protein 4;OTTHUMP00000161260
Cat.# Product name Source (Host) Species Tag Protein Length Price
NPAS2-2256C Recombinant Chicken NPAS2 Mammalian Cells Chicken His
NPAS2-9595Z Recombinant Zebrafish NPAS2 Mammalian Cells Zebrafish His
NPAS2-1208HCL Recombinant Human NPAS2 cell lysate Human Non
NPAS2-6015H Recombinant Human NPAS2 Protein, GST-tagged Wheat Germ Human GST
NPAS2-6606HF Recombinant Full Length Human NPAS2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 824 amino acids

    Involved Pathway

    NPAS2 involved in several pathways and played different roles in them. We selected most pathways NPAS2 participated on our site, such as Circadian rhythm, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPAS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Circadian rhythm PRKAG1,RORB,CLOCK,CRY1,PRKAA2,CSNK1E,BHLHE40,RORC,FBXW11,ARNTL

    Protein Function

    NPAS2 has several biochemical functions, for example, DNA binding,Hsp90 protein binding,core promoter binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NPAS2 itself. We selected most functions NPAS2 had, and list some proteins which have the same functions with NPAS2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding HSPB11,CDX4,RAB39A,STAG2,KIAA1958,FGF7,CHD7,SV2B,TRIP10,HTR3A
    metal ion binding FIZ1,ZBTB2B,CYP2K22,BLF,ZNF680,CYP46A1.3,TEC,FKBP8,HDDC3,CYP2AA1
    DNA binding ZNF222,ZNF446,SAP30,SIX4,ZFAND3,FOXQ1B,ARID5A,EXO1,MYCL1,LIN28A
    core promoter binding CRY1,SPI1,NOTCH1,AGO2,ELK4,CCAR1,EZH2,RB1,GTF2B,INSM1B
    Hsp90 protein binding HIF1A,ERN1,ARNTL,TELO2,RPS3,UNC45A,USP19,CHORDC1,FKBP6,AHR
    protein dimerization activity CLOCKA,FIGLA,NCOA1,CREB3,ATM,TFAP2C,MITF,ANO4,NEUROD4,MYCS
    transcription factor activity, sequence-specific DNA binding RARAA,ZKSCAN6,ZNF789,DMRT2B,TBX1,DMRTC2,ZNF227,EOMESB,HSFY1,RXRAA

    Interacting Protein

    NPAS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPAS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPAS2.

    Clock;BHLHE40;RORC;CSNK2B;Cry1;RPL6;Cry2;Arntl

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