NOX5
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Official Full Name
NADPH oxidase, EF-hand calcium binding domain 5 -
Overview
This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. -
Synonyms
NOX5;NADPH oxidase, EF-hand calcium binding domain 5;NADPH oxidase 5;NOX5A;NOX5B;MGC149776;MGC149777
Recombinant Proteins
- Human
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His&T7
- His
- Non
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NOX5-2797H | Recombinant Human NOX5 protein, His & T7-tagged | E.coli | Human | His&T7 | Ser456~Phe765 |
|
| NOX5-3726C | Recombinant Chicken NOX5 | Mammalian Cells | Chicken | His |
|
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| NOX5-3750HCL | Recombinant Human NOX5 293 Cell Lysate | HEK293 | Human | Non |
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| NOX5-5176H | Recombinant Human NOX5 Protein (Ser456-Phe765), N-His tagged | E.coli | Human | His | Ser456-Phe765 |
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| NOX5-6009H | Recombinant Human NOX5 Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| NOX5-6723HF | Recombinant Full Length Human NOX5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 747 amino acids |
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| RFL11578HF | Recombinant Full Length Human Nadph Oxidase 5(Nox5) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-765) |
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Involved Pathway
NOX5 involved in several pathways and played different roles in them. We selected most pathways NOX5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NOX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NOX5 has several biochemical functions, for example, NADP binding,calcium ion binding,flavin adenine dinucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOX5 itself. We selected most functions NOX5 had, and list some proteins which have the same functions with NOX5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| superoxide-generating NADPH oxidase activity | SH3PXD2AA,NOX1,NCF1,CYBB,PAX2,NOX3,NOX4 |
| heme binding | CYP3C1,TDO2B,CYP2C39,HBAA1,CBSA,CYBB,CYP4B1,CYP2C55,HBD,PTGES2 |
| NADP binding | DPYD,NOX1,CAT,GAPDH,SPR,GSR,POR,G6PD,NOS1,NDOR1 |
| hydrogen ion channel activity | ACCN5,SLC4A11,ASIC5 |
| protein binding | RPP38,UFC1,HTRA2,RNF146,P4HA3,AKR1B10,USP49,SIAH2,SLX4IP,MXD3 |
| flavin adenine dinucleotide binding | PPOX,GCDHA,SQLE,SDHA,TXNRD3,MTRR,FMO3,D2HGDH,FMO2,SQLEA |
| calcium ion binding | MAN1A1,NCAN,LTBP3,CAPN2B,F9,LCP1,SCUBE1,MMP17,CMLC1,MASP1 |
Interacting Protein
NOX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NOX5.
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