NMI
-
Official Full Name
N-myc (and STAT) interactor -
Overview
NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. -
Synonyms
NMI;N-myc (and STAT) interactor;N-myc-interactor;N-myc interactor
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- N-His-GST&C-Myc
- Myc&DDK
- GST
Involved Pathway
NMI involved in several pathways and played different roles in them. We selected most pathways NMI participated on our site, such as IL-2 Signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IL-2 Signaling Pathway | CD53,ITM2BA,SHB,CISH |
Protein Function
NMI has several biochemical functions, for example, protein binding,transcription cofactor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMI itself. We selected most functions NMI had, and list some proteins which have the same functions with NMI. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription cofactor activity | THRAP3,ZNF671,POU2AF1,ZFP710,ZNF710A,NRG1,MED12,FAM48A,LDB2,LDB2B |
| protein binding | NOP10,MYOG,CUL4B,CDC42BPA,LBH,NAIF1,YY1A,BANP,MYLK2,PKM2 |
Interacting Protein
NMI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMI here. Most of them are supplied by our site. Hope this information will be useful for your research of NMI.
SNAPC5;HHLA3;TRAF5;SCEL;HDDC3
Resources
Related Services
Related Products
References
- Vujicic, AD; Gemovic, B; et al. Natural autoantibodies in healthy neonatals recognizing a peptide derived from the second conserved region of HIV-1 gp120. VOJNOSANITETSKI PREGLED 71:352-361(2014).
- Sivridis, E; Koukourakis, MI; et al. Patterns of autophagy in urothelial cell carcinomas-the significance of "stone-like" structures (SLS) in transurethral resection biopsies. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS 31:1254-1260(2013).
