NMD3

  • Official Full Name

    NMD3 homolog

  • Overview

    Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm;through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1;;MIM 602559) pathway (Trotta et al., 2003 (PubMed 12773398)).

  • Synonyms

    NMD3;NMD3 homolog (S. cerevisiae);60S ribosomal export protein NMD3;CGI 07;hNMD3;CGI-07;FLJ21053

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • Myc&DDK
  • GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NMD3-1309H Recombinant Human NMD3, His-tagged E.coli Human His 154-503aa
NMD3-1031H Recombinant Human NMD3 Mammalian Cells Human His
NMD3-10737M Recombinant Mouse NMD3 Protein Mammalian Cells Mouse His
NMD3-2222Z Recombinant Zebrafish NMD3 Mammalian Cells Zebrafish His
NMD3-28547TH Recombinant Human NMD3, His-tagged E.coli Human His Full L. 1-503 a.a.
NMD3-3793HCL Recombinant Human NMD3 293 Cell Lysate HEK293 Human Non
NMD3-1569H Recombinant Human NMD3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
NMD3-301639H Recombinant Human NMD3 protein, GST-tagged E.coli Human GST Lys154-Thr503
NMD3-3642H Recombinant Human NMD3 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
NMD3-3642H-B Recombinant Human NMD3 Protein Pre-coupled Magnetic Beads HEK293 Human
NMD3-5923H Recombinant Human NMD3 Protein, GST-tagged Wheat Germ Human GST
NMD3-6107M Recombinant Mouse NMD3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NMD3-6107M-B Recombinant Mouse NMD3 Protein Pre-coupled Magnetic Beads HEK293 Mouse
NMD3-6757HF Recombinant Full Length Human NMD3 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 503 amino acids

    Involved Pathway

    NMD3 involved in several pathways and played different roles in them. We selected most pathways NMD3 participated on our site, such as Ribosome biogenesis in eukaryotes,RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport RPP14,EIF3HB,SRRM1,XPO5,THOC1,THOC3,NUPL1,KPNB1,RPP25,TRNT1
    Ribosome biogenesis in eukaryotes NAT10,PWP2H,LOC81691,ACK2,LSG1,NXT2,UTP14C,HEATR1,FCF1,NOB1

    Protein Function

    NMD3 has several biochemical functions, for example, poly(A) RNA binding,protein binding, bridging,ribosomal large subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NMD3 itself. We selected most functions NMD3 had, and list some proteins which have the same functions with NMD3. You can find most of the proteins on our site.

    Function Related Protein
    ribosomal large subunit binding NPM1,EIF6,MRRF,CPEB2,MALSU1,RBM3,OLA1
    poly(A) RNA binding NOM1,FRG1,FASN,MRPS23,SLTM,PEF1,DDX31,MRPL40,DCN,FKBP3
    protein binding, bridging EVPL,TRIM17,NEFH,TIRAP,TRIM22,MEN1,CBX5,TNNT2A,PPP2R3A,COL8A2

    Interacting Protein

    NMD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMD3.

    CSNK2A1;OTUD4;SLX4

    Resources

    References

    • Liu', ZH; Guo, JF; et al. Analysis of several loci from genome-wide association studies in Parkinson's disease in mainland China. NEUROSCIENCE LETTERS 587:68-71(2015).
    • Merwin, JR; Bogar, LB; et al. Genetic Analysis of the Ribosome Biogenesis Factor Ltv1 of Saccharomyces cerevisiae. GENETICS 198:1071-1085(2014).

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