NLRP9
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Official Full Name
NLR family, pyrin domain containing 9 -
Overview
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. -
Synonyms
NLRP9;NLR family, pyrin domain containing 9;NACHT, leucine rich repeat and PYD containing 9 , NALP9;NACHT, LRR and PYD domains-containing protein 9;CLR19.1;NOD6;nucleotide binding oligomerization domain;leucine rich repeat and pyrin domain containi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| NLRP9-3052R | Recombinant Rhesus monkey NLRP9 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| NLRP9-2871R | Recombinant Rhesus Macaque NLRP9 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| NLRP9-2871R-B | Recombinant Rhesus Macaque NLRP9 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
NLRP9 involved in several pathways and played different roles in them. We selected most pathways NLRP9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NLRP9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NLRP9 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NLRP9 itself. We selected most functions NLRP9 had, and list some proteins which have the same functions with NLRP9. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
NLRP9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLRP9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLRP9.
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References
- Silva, GK; Costa, RS; et al. Apoptosis-Associated Speck-like Protein Containing a Caspase Recruitment Domain Inflammasomes Mediate IL-1 beta Response and Host Resistance to Trypanosoma cruzi Infection. JOURNAL OF IMMUNOLOGY 191:3373-3383(2013).
- Grigoryev, DN; Howell, MD; et al. Vaccinia virus-specific molecular signature in atopic dermatitis skin. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 125:153-159(2010).
