NKAP

  • Official Full Name

    NFKB activating protein

  • Overview

    This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.

  • Synonyms

    NKAP;NFKB activating protein;NF-kappa-B-activating protein;FLJ22626;NF kappaB activating protein;NF-kappaB activating protein

Recombinant Proteins

  • Chicken
  • Rhesus macaque
  • Rat
  • Human
  • Zebrafish
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • E.coli
  • His
  • GST
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NKAP-1578C Recombinant Chicken NKAP Mammalian Cells Chicken His
NKAP-3032R Recombinant Rhesus monkey NKAP Protein, His-tagged Mammalian Cells Rhesus macaque His
NKAP-3992R Recombinant Rat NKAP Protein Mammalian Cells Rat His
NKAP-435H Recombinant Human NKAP Mammalian Cells Human His
NKAP-436H Recombinant Human NKAP Protein, GST-tagged Wheat Germ Human GST 1 a.a. - 415 a.a.
NKAP-867Z Recombinant Zebrafish NKAP Mammalian Cells Zebrafish His
NKAP-3820HCL Recombinant Human NKAP 293 Cell Lysate HEK293 Human Non
NKAP-1736HF Recombinant Full Length Human NKAP Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 415 amino acids
Nkap-1831R Recombinant Rat Nkap Protein, His-tagged E.coli Rat His Phe273-Lys415
NKAP-2851R Recombinant Rhesus Macaque NKAP Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
NKAP-2851R-B Recombinant Rhesus Macaque NKAP Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
NKAP-3626H Recombinant Human NKAP Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
NKAP-3626H-B Recombinant Human NKAP Protein Pre-coupled Magnetic Beads HEK293 Human
NKAP-3651R Recombinant Rat NKAP Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
NKAP-3651R-B Recombinant Rat NKAP Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    NKAP involved in several pathways and played different roles in them. We selected most pathways NKAP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    NKAP has several biochemical functions, for example, chromatin DNA binding,chromatin binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKAP itself. We selected most functions NKAP had, and list some proteins which have the same functions with NKAP. You can find most of the proteins on our site.

    Function Related Protein
    chromatin DNA binding THRA,H2AFY,ZIC2,MYOG,RARA,SLAMF7,PPARGC1A,H2AFY2,GATA1,APEX1
    chromatin binding DHX30,JMJD5,GLI1,Ar,NR5A2,STAG1,HDAC3,CENPB,MEN1,TGIF1
    protein binding UBE2U,CACNB4,NKD1,PLGRKT,PPP1R8,HNRNPA1,BLOC1S2A,RPS19BP1,CLASP1,POLRMT
    poly(A) RNA binding NMD3,PUS7,FBL,CHST13,LTA4H,NOA1,DDX39,SRSF10,SRSF7,RSRC2

    Interacting Protein

    NKAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKAP here. Most of them are supplied by our site. Hope this information will be useful for your research of NKAP.

    PRPF3;PRPF40A;U2AF1;DHX8;DDX41;RBMX2;tax;SRPK1;RNPS1;Ddx41;DHX15;BUB3;NOS1AP

    NKAP Related Signal Pathway

    Resources

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