NIPA2

  • Official Full Name

    non imprinted in Prader-Willi/Angelman syndrome 2

  • Overview

    This gene encodes a possible magnesium transporter. This gene is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 7 and 21.

  • Synonyms

    NIPA2;non imprinted in Prader-Willi/Angelman syndrome 2;magnesium transporter NIPA2;MGC5466;NIPA 2;Non imprinted in Prader Willi/Angelman syndrome 2;Non imprinted in Prader Willi/Angelman syndrome region protein 2;non-imprinted in Prader-Willi/Angelman syndrome region protein 2

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Chicken
  • Rhesus macaque
  • Mammalian Cells
  • HEK293
  • His
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NIPA2-10671M Recombinant Mouse NIPA2 Protein Mammalian Cells Mouse His
NIPA2-12343Z Recombinant Zebrafish NIPA2 Mammalian Cells Zebrafish His
NIPA2-2507C Recombinant Chicken NIPA2 Mammalian Cells Chicken His
NIPA2-3031R Recombinant Rhesus monkey NIPA2 Protein, His-tagged Mammalian Cells Rhesus macaque His
NIPA2-8254Z Recombinant Zebrafish NIPA2 Mammalian Cells Zebrafish His
NIPA2-2850R Recombinant Rhesus Macaque NIPA2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
NIPA2-2850R-B Recombinant Rhesus Macaque NIPA2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
NIPA2-6069M Recombinant Mouse NIPA2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NIPA2-6069M-B Recombinant Mouse NIPA2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NIPA2 involved in several pathways and played different roles in them. We selected most pathways NIPA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NIPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    NIPA2 has several biochemical functions, for example, magnesium ion transmembrane transporter activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NIPA2 itself. We selected most functions NIPA2 had, and list some proteins which have the same functions with NIPA2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding Serpina1b,EFEMP1,GPR125,TEX19.1,Arid4b,RRM2B,ZNF576,DYNLT1,XRCC5,KLRG1
    magnesium ion transmembrane transporter activity NIPA1,MMGT1,CNNM4,TUSC3,NIPAL4,NIPAL3,ZDHHC17,MRS2,CLDN16,MMGT2

    Interacting Protein

    NIPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NIPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NIPA2.

    cj035_mouse

    Resources

    References

    • Xie, H; Zhang, YH; et al. Functional Study of NIPA2 Mutations Identified from the Patients with Childhood Absence Epilepsy. PLOS ONE 9:-(2014).
    • Van Blitterswijk, M; Mullen, B; et al. Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers. NEUROBIOLOGY OF AGING 35:-(2014).

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