NID2
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Official Full Name
nidogen 2 -
Overview
Nidogen-2 is a protein that in humans is encoded by the NID2 gene. Basement membranes, which are composed of type IV collagens (see MIM 120130), laminins (see LAMC1; MIM 150290), perlecan (HSPG2; MIM 142461), and nidogen (see NID1; MIM 131390), are thin pericellular protein matrices that control a large number of cellular activities, including adhesion, migration, differentiation, gene expression, and apoptosis.[supplied by OMIM -
Synonyms
Nid2;nidogen2;Ly111;NID-2;AW547149;nidogen-2;entactin-2;osteonidogen2;nidogen 2 (osteonidogen)
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- Yeast
- His
- Non
- His&Fc&Avi
- Fc
- N-His&C-Myc
Involved Pathway
NID2 involved in several pathways and played different roles in them. We selected most pathways NID2 participated on our site, such as Extracellular matrix organization,Laminin interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with NID2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Extracellular matrix organization | LAMB1B,CTS7,MMP24,FBLN2,VCANB,LOX,LOXL1,FMOD,COL10A1A,MATN4 |
| Laminin interactions | LAMC3,NID1,LAMB1B |
Protein Function
NID2 has several biochemical functions, for example, calcium ion binding,collagen binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NID2 itself. We selected most functions NID2 had, and list some proteins which have the same functions with NID2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CLPTM1,GLP1R,LRRC26,PARK2,HLX,XPA,CSRP2,WRN,PROC,MOAP1 |
| collagen binding | RELL2,Itga10&Itgb1,LUM,MRC2,PODN,ITGA1,MMP9,DDR2,SERPINH1,PDGFB |
| calcium ion binding | OVAL,LDLR,MEX3B,PLCD3A,NECAB1,DGKAA,PCLO,PCDHB11,VLDLR,NCALD |
Interacting Protein
NID2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NID2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NID2.
SKIL;q9wmx2-pro_0000037548
Resources
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References
- Britze, A; Birkler, RID; et al. Large-Scale Proteomics Differentiates Cholesteatoma from Surrounding Tissues and Identifies Novel Proteins Related to the Pathogenesis. PLOS ONE 9:-(2014).
- Maldonado, L; Brait, M; et al. An epigenetic marker panel for recurrence risk prediction of low grade papillary urothelial cell carcinoma (LGPUCC) and its potential use for surveillance after transurethral resection using urine. ONCOTARGET 5:5218-5233(2014).
