NFS1
-
Official Full Name
NFS1 nitrogen fixation 1 homolog (S. cerevisiae) -
Overview
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. -
Synonyms
NFS1;NFS1 nitrogen fixation 1 homolog (S. cerevisiae);nitrogen fixation 1 (S. cerevisiae, homolog);cysteine desulfurase, mitochondrial;IscS;NifS;HUSSY 08;nitrogen fixation gene 1;OTTHUMP00000030799;OTTHUMP00000030800;OTTHUMP00000179026;nitrogen-fixing bacteria S-like protein;HUSSY-08
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NFS1-2543C | Recombinant Chicken NFS1 | Mammalian Cells | Chicken | His |
|
|
| NFS1-4074Z | Recombinant Zebrafish NFS1 | Mammalian Cells | Zebrafish | His |
|
|
| NFS1-3844HCL | Recombinant Human NFS1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| NFS1-01H | Recombinant Human NFS1 protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| NFS1-02H | Recombinant Human NFS1 protein, GST-tagged | Wheat Germ | Human | GST | 1-457aa |
|
Involved Pathway
NFS1 involved in several pathways and played different roles in them. We selected most pathways NFS1 participated on our site, such as Thiamine metabolism,Metabolic pathways,Sulfur relay system, which may be useful for your reference. Also, other proteins which involved in the same pathway with NFS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Thiamine metabolism | NTPCR,THTPA,TPK1 |
| Metabolic pathways | HMGCRA,DNMT3AA,DHRS4L2,ATP6V0A1A,SGPL1,INPP4A,QDPRB1,COASY,NME1,CYP2A4 |
| Sulfur relay system | CTU2,LBH,TRMU,MOCS2,MPST,MOCS3,CTU1,MOCS1,TST,URM1 |
Protein Function
NFS1 has several biochemical functions, for example, cysteine desulfurase activity,iron-sulfur cluster binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NFS1 itself. We selected most functions NFS1 had, and list some proteins which have the same functions with NFS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| iron-sulfur cluster binding | REV3L,FXN,RSAD1,NUBP1,NDUFS1,AOX3L1,PROZA,ELP3,DPYDB,RTEL1 |
| protein homodimerization activity | USH2A,HPGD,TAP1,DMRT2A,CARD8,NBL1,MAP3K13,QDPR,DMRTA1,ASCL1 |
| metal ion binding | OSR1,ZDHHC23B,MBNL2,ZNF280A,FAM96A,SP9,PRDM5,CNOT6L,CNBPA,CTH1 |
| protein binding | CHAF1A,FIBPB,LGALS2,ZFC3H1,CCNE2,TRMT112,RAB10,MTIF3,SGOL2,RHOG |
| pyridoxal phosphate binding | SRR,KYNU,GOT1L1,CTHL,PDXK,ALAS2,SPTLC1,PYGMA,CTH,PHYKPL |
Interacting Protein
NFS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NFS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NFS1.
ABL1;FYN;GRB2;CLPP;RB1CC1
Resources
Related Services
Related Products
References
