Nell2

  • Official Full Name

    NEL-like 2 (chicken)

  • Overview

    The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]

  • Synonyms

    NELL2;NEL-like 2 (chicken);NRP2;protein kinase C-binding protein NELL2;NEL-like protein 2;NEL-related protein 2;neural epidermal growth factor-like 2

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • Insect Cells
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&T7
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
NELL2-1262H Recombinant Human NELL2, GST-tagged E.coli Human GST 443-740aa
NELL2-2441C Recombinant Chicken NELL2 Mammalian Cells Chicken His
NELL2-29300TH Recombinant Human NELL2 Wheat Germ Human Non 816 amino acids
NELL2-29302TH Recombinant Human NELL2 Wheat Germ Human Non 100 amino acids
NELL2-3001R Recombinant Rhesus monkey NELL2 Protein, His-tagged Mammalian Cells Rhesus macaque His
Nell2-394M Recombinant Mouse NEL-like 2 (Chicken), His-tagged E.coli Mouse His
NELL2-492H Recombinant Human NELL2 Protein, His-tagged Insect Cells Human His 1-816 a.a.
NELL2-468HCL Recombinant Human NELL2 cell lysate Insect Cells Human Non
NELL2-1915H Recombinant Human NELL2 protein, His & T7-tagged E.coli Human His&T7 Pro64~Lys331
NELL2-2820R Recombinant Rhesus Macaque NELL2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
NELL2-2820R-B Recombinant Rhesus Macaque NELL2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
NELL2-337HF Recombinant Full Length Human NELL2 Protein In Vitro Cell Free System Human Full L. 816 amino acids
Nell2-4374M Recombinant Mouse Nell2 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
NELL2-4683H Recombinant Human NELL2 Protein (Pro64-Lys331), N-His tagged E.coli Human His Pro64-Lys331
NELL2-6562H Recombinant Human NELL2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
NELL2-758H Recombinant Human NELL2 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK

    Involved Pathway

    Nell2 involved in several pathways and played different roles in them. We selected most pathways Nell2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Nell2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    Nell2 has several biochemical functions, for example, calcium ion binding,heparin binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Nell2 itself. We selected most functions Nell2 had, and list some proteins which have the same functions with Nell2. You can find most of the proteins on our site.

    Function Related Protein
    heparin binding PDCD5,WISP1,CRISPLD2,SFRP1,AZU1,RPL22,SLIT1,COL20A1,Epy,MMP7
    calcium ion binding CALM3,PLCD1,KCNIP3B,EFEMP2,ICN2,NRXN1,LTBP2,FLG2,DGKG,CRELD2
    protein kinase C binding YWHAG,PKN1,PARD3,AKT1,TDG,PEA15A,SDPR,HINT1,CASQ2,TIRAP
    protein binding STX4,POU2F3,NEK1,PIK3IP1,HNRPDL,JAK2,GABRG2,CYB5R2,CALML3,PLEKHG4
    identical protein binding RABAC1,SF1,DAPK1,P2RX6,MICU1,PLN,PDCD6,CCDC109A,CHAF1A,APIP

    Interacting Protein

    Nell2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nell2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Nell2.

    GFI1B;CACNA1A;ATXN7;PRKAR1A;ATN1;ompA4;q8ckw7_yerpe;mdtB;q9wmx2-pro_0000037548

    Resources

    Research Area

    Neuronal Lineage Markers

    References

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