NDUFS7

  • Official Full Name

    NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

  • Overview

    This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain.;This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone;oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone;is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to;mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic;lesions in subcortical brain regions.

  • Synonyms

    NDUFS7;NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase);NADH dehydrogenase (ubiquinone) Fe S protein 7 (20kD) (NADH coenzyme Q reductase);CI 20;complex I 20kDa subunit;FLJ45860;FLJ46880;NADH dehydrogenase [ubiquinon

Recombinant Proteins

  • Mouse
  • Human
  • Zebrafish
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
NDUFS7-10547M Recombinant Mouse NDUFS7 Protein Mammalian Cells Mouse His
NDUFS7-562H Recombinant Human NDUFS7 Mammalian Cells Human His
NDUFS7-7890Z Recombinant Zebrafish NDUFS7 Mammalian Cells Zebrafish His
NDUFS7-3893HCL Recombinant Human NDUFS7 293 Cell Lysate HEK293 Human Non
NDUFS7-3607H Recombinant Human NDUFS7 Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
NDUFS7-3607H-B Recombinant Human NDUFS7 Protein Pre-coupled Magnetic Beads HEK293 Human
NDUFS7-5993M Recombinant Mouse NDUFS7 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
NDUFS7-5993M-B Recombinant Mouse NDUFS7 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NDUFS7 involved in several pathways and played different roles in them. We selected most pathways NDUFS7 participated on our site, such as Alzheimers disease,Electron Transport Chain,Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFS7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism ELA2,NUDT16,FAM36A,GYG1A,UCP3,SLC16A8,COX5B,MED9,ETFB,ADA
    Oxidative phosphorylation COX10,NDUFS3,UQCR10,COX11,ATP4B,ATP6V0A1B,ATP6V1C1A,ATP5S,ATP6V0E2,LHPP
    Alzheimers disease NAE1,CDK5,COX6A1,UQCRB,COX5B,NDUFC2,BACE2,ADAM17,CALM4,ATP5G1
    Parkinsons disease COX4I2,PPIF,GNAI3,NDUFA5,SDHA,SEPT5,COX6B2,UQCRC1,UBE2G1,COX7B2
    Metabolic pathways ADH2-1,LDHAL6B,HSD3B5,UROC1,C1GALT1,PLA2G2E,GPAT2,PLA2G4D,ADH2-2,SDHC
    Electron Transport Chain ATPIF1,SLC25A27,COX6C,ATP5H,COX6A1,SLC25A14,SURF1,ATP5S,COX8A,COX5B
    Non-alcoholic fatty liver disease (NAFLD) NDUFB2,ATF4,COX8C,INSR,COX6A2,TNF,NDUFA4,NDUFV2,NDUFB9,PRKAG1
    Huntingtons disease NDUFA7,NDUFS1,NDUFS8,NDUFB3,POLR2J2,TAF4B,NDUFAB1,NDUFS3,VDAC1,NDUFB8

    Protein Function

    NDUFS7 has several biochemical functions, for example, 4 iron, 4 sulfur cluster binding,NADH dehydrogenase (ubiquinone) activity,contributes_to NADH dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFS7 itself. We selected most functions NDUFS7 had, and list some proteins which have the same functions with NDUFS7. You can find most of the proteins on our site.

    Function Related Protein
    NADH dehydrogenase (ubiquinone) activity NDUFA2,NDUFAF2,NDUFB10,NDUFV3,NDUFV2,NDUFA10,NDUFS6,NDUFC2-KCTD14,NDUFC2,NDUFS2
    quinone binding TP53I3,ETFDH,NDUFS2,HHIPL2,HHIPL1,HHIP,AOC1,CBR4,VKORC1,AOC3
    protease binding CCDC71L,FLOT1,RYR1,STIM1,FN1,ECM1,LDLR,TIMP3,ADRM1,ITGB3
    protein binding DBC1,TMEM11,PDLIM3,CCL20,F5,ATP6AP2,FAM119A,MED21,SYT7,TXNL4B
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor DHRS4,AKR1C3,AKR1C2,AKR1C4,AKR1C6,AKR1C21,DCXR,CBR1
    metal ion binding SALL3,CISD2,NCALDA,ZNF496,CIZ1B,Alb,IMPDH1,TMEM129,HMOX1,PLA2G4F
    contributes_to NADH dehydrogenase activity NDUFS8,NDUFS2,NDUFV1
    4 iron, 4 sulfur cluster binding NUBPL,TYW1,DEM1,ACO2,PRIM2,DPYD,RSAD2,NFU1,NDUFS2,ETFDH

    Interacting Protein

    NDUFS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFS7.

    NDUFA2;ENO2;ARRB2;NDUFS8;NDUFS5;NDUFS2;NDUFS3;SCO1;ETHE1;NQO1;NDUFS1;LONP1;NDUFA6;ALDH6A1;NDUFA5;NDUFA9;NDUFAF5

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