NDUFB4
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa -
Overview
This gene encodes a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first enzyme complex;in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits;and transfers electrons from NADH to ubiquinone. -
Synonyms
B15;CI-B15
Recombinant Proteins
- Mouse
- Zebrafish
- Rhesus macaque
- Human
- Chicken
- Pongo Abelii
- Pan troglodytes
- Bovine
- Pongo Pygmaeus
- Gorilla gorilla gorilla (Western lowland gorilla)
- Mus musculus
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
NDUFB4 involved in several pathways and played different roles in them. We selected most pathways NDUFB4 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Non-alcoholic fatty liver disease (NAFLD) | RAC1,PRKAG1,PRKAA2,UQCR10,COX5A,NDUFB7,ADIPOQ,PIK3R5,ITCH,MAPK9 |
| Alzheimers disease | GRIN2C,PLCB3,BACE1,COX8C,BACE2,COX8A,NDUFA3,ATP5J,ITPR3,UQCRB |
| Huntingtons disease | NDUFA3,RCOR1,Casp3,CASP8,NDUFA4L2,GRIN2B,NDUFA1,ATP5J,NDUFB10,NDUFB9 |
| Metabolic pathways | GCLC,PTGES2,GLULA,OGDH,ACO1,PIGN,GLUD1A,GLUD1,UQCRC1,NDUFA12 |
| Parkinsons disease | SDHA,GNAI1,ATP5J,COX7A2,NDUFB7,PPIF,SDHB,UQCRH,ATP5G1,NDUFB11 |
| Oxidative phosphorylation | MT-ND4,NDUFS8A,MT-ATP6,ATP6V1B1,NDUFA12,ATP6V0A1B,ATP5B,ATP6V1C1B,ATP5C1,ATP6V0D1 |
Protein Function
NDUFB4 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFB4 itself. We selected most functions NDUFB4 had, and list some proteins which have the same functions with NDUFB4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NADH dehydrogenase (ubiquinone) activity | NDUFS6,NDUFS5,NDUFB6,NDUFS4,NDUFV2,NDUFB3,NDUFB9,NDUFA3,NDUFS7,NDUFAF2 |
Interacting Protein
NDUFB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFB4.
NDUFS4;NDUFS5;NDUFS3;MME;NDUFV1;NDUFA6;NDUFA9;LRRK2;NDUFA11;TIMMDC1;NDUFA12
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