NDUFA11
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -
Overview
This gene encodes a subunit of the membrane-bound mitochondrial complex I. Complex I is composed of numerous subunits and functions as the NADH-ubiquinol reductase of the mitochondrial electron transport chain. Mutations in this gene are associated with severe mitochondrial complex I deficiency. Alternate splicing results in multiple transcript variants. -
Synonyms
NDUFA11;NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa;NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11;B14.7;complex I B14.7 subunit;FLJ76501;2010012C24Rik;AV006275;CI-B14.7;Complex I-B14.7;NADH-ubiquinone oxidoreductase subunit B14.7;NDUAB_HUMAN
Recombinant Proteins
- Zebrafish
- Rat
- Human
- Mus musculus
- Pongo Pygmaeus
- Gorilla gorilla gorilla (Western lowland gorilla)
- Bovine
- Pan troglodytes
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- Avi
- Fc
Involved Pathway
NDUFA11 involved in several pathways and played different roles in them. We selected most pathways NDUFA11 participated on our site, such as Alzheimers disease,Huntingtons disease,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFA11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ALDH3B2,TK1,ASAH1B,ALOX5A,NDUFA3,HYAL3,NADKB,GCDHA,GPAA1,P4HA1 |
| Oxidative phosphorylation | COX5B2,LHPP,ATP6V1C1,ATP6V1G2,ATP6V0D1,ATP6V0E,NDUFC2-KCTD14,COX7A1,NDUFC1,MT-ND1 |
| Huntingtons disease | NDUFB4,TAF4B,NDUFV3,UQCRQ,COX6B1,DNAHC8,NDUFA8,DNAH5,COX7A1,SLC25A6 |
| Parkinsons disease | MT-ND1,NDUFA10,COX6B2,UQCRH,NDUFB7,SDHB,NDUFC1,COX7A1,UQCR10,GNAI3 |
| Metabolism | GPAT2,FABP11A,SGMS2,B3GAT2,FAM36A,CTRB1,ACSF3,GLYATL2,LMF1,NUDT3 |
| Respiratory electron transport | SURF1,ETFB,LRPPRC,NDUFAF6,NDUFAF2,NDUFAF3,NDUFAF7,COX11,TACO1,COX14 |
| Non-alcoholic fatty liver disease (NAFLD) | COX7B2,NDUFA2,PRKAA1,NDUFA7,NDUFA8,MAP3K5,CDC42,Fasl,NDUFB10,PIK3CB |
| Alzheimers disease | APP,ATP5G1,BACE1,AKR1C1,ATF6,CDK5R1,UQCRFS1,COX4I2,UQCRC2,ADAM17 |
Protein Function
NDUFA11 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFA11 itself. We selected most functions NDUFA11 had, and list some proteins which have the same functions with NDUFA11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
NDUFA11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFA11 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFA11.
NDUFA2;NDUFA6;NDUFS8;NDUFAB1;NDUFS4;NDUFB5;NDUFB3;NDUFS5;NDUFS7;NDUFS2;NDUFS6;NDUFS3;NDUFB6;NDUFB4
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