NDST3

  • Official Full Name

    N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

  • Overview

    This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.

  • Synonyms

    NDST3;N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3;bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3;HSST3;Bifunctional heparan sulfate N deacetylase/N sulfotransferase 3;Glucosaminyl N deacetylase/N sulfotransferase 3;hNDST 3;hNDST3;HSST 3;MGC130028;MGC130029;N deacetylase/N sulfotransferase (heparan glucosaminyl) 3;N heparan sulfate sulfotransferase 3;N HSST 3;NDST 3;NDST-3;hNDST-3;N-HSST 3;OTTHUMP00000163902;N-heparan sulfate sulfotransferase 3;GlcNAc N-deacetylase/ N-sulfotransferase 3;glucosaminyl N-deacetylase/N-sulfotransferase 3
Cat.# Product name Source (Host) Species Tag Protein Length Price
NDST3-2971R Recombinant Rhesus monkey NDST3 Protein, His-tagged Mammalian Cells Rhesus macaque His
NDST3-3927HCL Recombinant Human NDST3 293 Cell Lysate HEK293 Human Non
NDST3-2678H Recombinant Human NDST3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
NDST3-2790R Recombinant Rhesus Macaque NDST3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
NDST3-2790R-B Recombinant Rhesus Macaque NDST3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Ndst3-4327M Recombinant Mouse Ndst3 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    NDST3 involved in several pathways and played different roles in them. We selected most pathways NDST3 participated on our site, such as Glycosaminoglycan biosynthesis - heparan sulfate / heparin,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDST3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways ALOX5A,B3GALT1,SDHDB,DAO.2,CEPT1,RIMKLB,P4HA2,GPT,HSD17B8,PPCS
    Glycosaminoglycan biosynthesis - heparan sulfate / heparin EXT1B,B4GALT7,HS3ST1L1,HS3ST3A1,HS3ST1,GLCE,B3GAT3,HS6ST1B,EXTL1,HS3ST2

    Protein Function

    NDST3 has several biochemical functions, for example, [heparan sulfate]-glucosamine N-sulfotransferase activity,deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDST3 itself. We selected most functions NDST3 had, and list some proteins which have the same functions with NDST3. You can find most of the proteins on our site.

    Function Related Protein
    deacetylase activity MACROD1,HDAC1,C6orf130,AADAC,NDST4,MAPK1IP1L,NDST1,MACROD2,SIRT1,HDAC2
    [heparan sulfate]-glucosamine N-sulfotransferase activity NDST1,MAPK1IP1L,NDST4,NDST2

    Interacting Protein

    NDST3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDST3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDST3.

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