NCAPD2

  • Official Full Name

    non-SMC condensin I complex, subunit D2

  • Overview

    CNAP1/hCAP-D2 is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. It may target the condensin complex to DNA via its C-terminal domain (referenced from Swissprot).

  • Synonyms

    NCAPD2;non-SMC condensin I complex, subunit D2;CNAP1;CAP-D2;hCAP-D2;condensin complex subunit 1;XCAP-D2 homolog;chromosome-associated protein D2;chromosome condensation related SMC associated protein 1;chromosome condensation-related SMC-associated protein 1

Recombinant Proteins

  • Mouse
  • Human
  • Chicken
  • Zebrafish
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NCAPD2-10456M Recombinant Mouse NCAPD2 Protein Mammalian Cells Mouse His
NCAPD2-1550H Recombinant Human NCAPD2 Protein, GST-tagged Wheat Germ Human GST
NCAPD2-3619C Recombinant Chicken NCAPD2 Mammalian Cells Chicken His
NCAPD2-7536Z Recombinant Zebrafish NCAPD2 Mammalian Cells Zebrafish His
NCAPD2-372HCL Recombinant Human NCAPD2 cell lysate Human Non
NCAPD2-5930M Recombinant Mouse NCAPD2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
NCAPD2-5930M-B Recombinant Mouse NCAPD2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    NCAPD2 involved in several pathways and played different roles in them. We selected most pathways NCAPD2 participated on our site, such as Aurora B signaling,Cell Cycle,Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCAPD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    M Phase STAG2,CTDNEP1,SETA,SPDL1,CDCA8,B9D2,WAPAL,STAG1,APITD1,SET
    Mitotic Prometaphase WAPAL,SMC2,B9D2,CENPC1,MLF1IP,SKA1,CDCA5,SKA2,SGOL1,SPC25
    Aurora B signaling NSUN2,PEBP1,NDC80,TACC1,CDCA8,NCAPH,AURKB,DES,RACGAP1,EVI5
    Condensation of Prometaphase Chromosomes CSNK2A2,CSNK2B,SMC2,SMC4,NCAPH,CSNK2A1,NCAPG
    Cell cycle E2F6,CDKN1B,E2F5,SMC1AL,TERF1,MYBL2,E2F2,HJURP,CEP164,TGFB1
    Cell Cycle, Mitotic NEK7,DBF4,SPDL1,CENPE,NIPBLB,GINS4,MASTL,PCM1,TOP2A,TUBG2

    Protein Function

    NCAPD2 has several biochemical functions, for example, chromatin binding,histone binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCAPD2 itself. We selected most functions NCAPD2 had, and list some proteins which have the same functions with NCAPD2. You can find most of the proteins on our site.

    Function Related Protein
    histone binding RAG1,UHRF1,CHD8,HIST1H4H,H3F3B,NCAPD3,HIST1H4M,SFMBT1,SMARCA2,HIST2H3C1
    chromatin binding RBMX,TP73,DNAJC2,NEUROD1,ING5,ARID3C,ZGLP1,BRD4,RBPJ,LMO2
    protein binding PTGDR,BTF3,DLG4,IRF1,KLF6,EIF2AK2,MAP3K4,COMMD2,TNFAIP8L1,EXOSC3

    Interacting Protein

    NCAPD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCAPD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCAPD2.

    NCAPH;CSNK2A1;SMC2;NCAPG;NEK6;q8ck80_yerpe;SNW1;Ncaph;Smc4;CDC5L

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