MYOM2
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Official Full Name
myomesin (M-protein) 2, 165kDa -
Overview
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. -
Synonyms
MYOM2;myomesin (M-protein) 2, 165kDa;myomesin (M protein) 2 (165kD);myomesin-2;M-protein;M-band protein;myomesin family member 2;165 kDa titin-associated protein;titin-associated protein, 165 kD;165 kDa connectin-associated protein;TTNAP
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MYOM2-799H | Recombinant Human MYOM2 Protein, His-tagged | E.coli | Human | His | Pro1130~Ser1434 | |
| MYOM2-6692C | Recombinant Chicken MYOM2 | Mammalian Cells | Chicken | His |
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Involved Pathway
MYOM2 involved in several pathways and played different roles in them. We selected most pathways MYOM2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MYOM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MYOM2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MYOM2 itself. We selected most functions MYOM2 had, and list some proteins which have the same functions with MYOM2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MYOM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYOM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYOM2.
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References
- Ashton, KJ; Tupicoff, A; et al. Unique Transcriptional Profile of Sustained Ligand-Activated Preconditioning in Pre- and Post-Ischemic Myocardium. PLOS ONE 8:-(2013).
- Perrot, A; Barton, A; et al. Is the gene MYOM2 encoding myomesin 2 involved in the pathogenesis of hypertrophic cardiomyopathy?. EUROPEAN HEART JOURNAL 33:859-860(2012).
