MYLIP
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Official Full Name
myosin regulatory light chain interacting protein -
Overview
The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP) is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth. -
Synonyms
MYLIP;myosin regulatory light chain interacting protein;E3 ubiquitin-protein ligase MYLIP;E3 ubiquitin ligase inducible degrader of the low density lipoprotein receptor;IDOL;MIR;band 4.1 superfamily member BZF1;inducible degrader of the LDL-recepto
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Human
- Mammalian Cells
- HEK293
- E.coli
- Yeast
- E. coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- GST
- Avi
- Fc
Involved Pathway
MYLIP involved in several pathways and played different roles in them. We selected most pathways MYLIP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MYLIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MYLIP has several biochemical functions, for example, cytoskeletal protein binding,ligase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYLIP itself. We selected most functions MYLIP had, and list some proteins which have the same functions with MYLIP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | PLCG2,SLC38A2,DOK1,DUSP1,STUB1,PPM1G,ETNK1,USP49,ARPC5,TESC |
| cytoskeletal protein binding | SLC8A1,LDB3,PACSIN1A,PTPN4B,EPB41L5,EPB41L4A,MSNA,EPB4.1L4A,EZRA,FRMD3 |
| ubiquitin protein ligase activity | UBR1,CDC42,FBXO40,RNF165,SIAH1,FBXO6,TRIM32,MED10,DZIP3,PDZD4 |
| ligase activity | BIRC3,SIAH2,RNF169,NSMCE2,TRIM63,NEDD4,RAD18,UBE2D1A,RNF40,ITCH |
| ubiquitin-protein transferase activity | KLHL20,NSMCE1,RNF135,PAX6,PDZRN3B,UBE2G2,FBXO7,RNF41,STUB1,UBE2C |
| zinc ion binding | PRDM2,ZNF212,KDM5BB,XIAP,NEIL3,MMP11,EP300,MT1H,TRIM46B,GTF2H2 |
Interacting Protein
MYLIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYLIP here. Most of them are supplied by our site. Hope this information will be useful for your research of MYLIP.
MIPOL1;RASSF5;TSC22D4;CNPY2;CRK;DAPP1;KDM1A;LNX2
Resources
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References
- Sulbaran, G; Biasutto, A; et al. Different Head Environments in Tarantula Thick Filaments Support a Cooperative Activation Process. BIOPHYSICAL JOURNAL 105:2114-2122(2013).
- Xu, J; Yang, GM; et al. INVOLVEMENT OF CPI-17 AND ZIPPER-INTERACTING PROTEIN KINASE IN THE REGULATION OF PROTEIN KINASE C-alpha, PROTEIN KINASE C-epsilon ON VASCULAR CALCIUM SENSITIVITY AFTER HEMORRHAGIC SHOCK. SHOCK 33:49-55(2010).
