MYBL2
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Official Full Name
v-myb myeloblastosis viral oncogene homolog (avian)-like 2 -
Overview
The Myb family of transcrIPPtion factors includes A-Myb, B-Myb and c-Myb.1 B-Myb is involved in controlling cell proliferation and differentiation.1-4 B- Myb expression is widespread, and is detectable in stomach, lung, colon, and thyroid carcinoma and ne -
Synonyms
MYBL2;v-myb myeloblastosis viral oncogene homolog (avian)-like 2;v myb avian myeloblastosis viral oncogene homolog like 2;myb-related protein B;B MYB;BMYB;myb-like protein 2;v-myb avian myeloblastosis viral oncogene homolog-like 2;B-MYB;MGC15600
Recombinant Proteins
- Rhesus macaque
- Chicken
- Human
- Mouse
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
- GST
Involved Pathway
MYBL2 involved in several pathways and played different roles in them. We selected most pathways MYBL2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,E2F transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYBL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | TUBGCP4,SMAD3B,SMC1AL,DCTN1A,ODF2,CENPP,RAD9B,ANAPC5,CLSPN,BRCC3 |
| HTLV-I infection | VDAC1,NFATC1,CD3E; CD3D,HLA-E,SLC2A1,PIK3CA,WNT9B,RAN,WNT6,H2-AA |
| Gastric cancer network 1 | TOP2A,LIN9,ESM1,S100P,ACTL6A,SMOC2,RNF216,TPX2,ECT2,C21orf33 |
| Cell Cycle, Mitotic | KIF18A,GORASP1,NIPBLB,KIF20A,TUBG2,SETA,VRK2,TUBGCP3,TCTN2,STAG1 |
| G0 and Early G1 | LIN37,TOP2A,LIN54,PIANP,LIN52,E2F4,DYRK1A,LIN9 |
| E2F transcription factor network | YY1,HBP1,E2F6,CDKN2C,RYBP,CES1,RBBP8,CEBPA,CES5A,CES3 |
| G2/M Transition | DCTN2,NUMA1,NINL,CEP70,MAPRE1B,CKAP5,SSNA1,DCTN3,LIN37,CDK11A |
| Mitotic G1-G1/S phases | LIN52,LIN37,LIN9,MYCA,DYRK1A,LIN54,TOP2A |
Protein Function
MYBL2 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYBL2 itself. We selected most functions MYBL2 had, and list some proteins which have the same functions with MYBL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | GBA,TPM1,PPP6R3,ZNF385C,HIST1H2AK,PLEKHG2,TACR2,CARD11,RXFP4,ZC3H15 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TFAM,ETV6,STAT3,TFAP2B,SMAD1,NEUROG3,ONECUTL,GCM1,FLI1,FOXK2 |
| transcription factor activity, sequence-specific DNA binding | ZNF615,HSF1,NFKB2,HIVEP2A,NFATC1,ZFP518A,ZNF549,ZBTB14,SIM1B,ZFP13 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | KLF5,NRL,NR6A1,JUNBA,CEBPA,MAX,GCFC2,SP1,ZSCAN21,HNRNPK |
Interacting Protein
MYBL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYBL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYBL2.
LIN9;LIN54;E2F3;E2F4;Lin54;HDAC2;CXCR4;MAPK6;MAP1LC3B;TTF2;UBE2D4
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