MUC20

  • Official Full Name

    mucin 20, cell surface associated

  • Overview

    This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    MUC20;mucin 20, cell surface associated;mucin-20;FLJ14408;KIAA1359;MUC 20;MUC-20;MUC20_HUMAN;Mucin 20;Transmembrane mucin MUC20S
Cat.# Product name Source (Host) Species Tag Protein Length Price
MUC20-1108H Recombinant Human MUC20, GST-tagged E.coli Human GST 255-555aa
Muc20-5711R Recombinant Rat Muc20 protein, His & GST-tagged E.coli Rat GST&His Thr113~Asn347
MUC20-1154HCL Recombinant Human MUC20 cell lysate Human Non
Muc20-1804M Recombinant Mouse Muc20 Protein, His-tagged E.coli Mouse His Thr399-Asp603
MUC20-5749H Recombinant Human MUC20 Protein, GST-tagged Wheat Germ Human GST
MUC20-6521HF Recombinant Full Length Human MUC20 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 538 amino acids

    Involved Pathway

    MUC20 involved in several pathways and played different roles in them. We selected most pathways MUC20 participated on our site, such as Metabolism of proteins,O-linked glycosylation,O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Termination of O-glycan biosynthesis MUCL1,MUC1,MUC4,MUC12,MUC13,MUC15,MUC5AC,MUC21
    Post-translational protein modification ARSF,ARSK,GALNT13,ADAMTS13,SCMH1,MGAT4B,CNIH,THSD7A,ADAMTS15,PROZ
    Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) DEPDC6
    O-linked glycosylation ST6GALNAC2,GALNTL5,ADAMTS8,ADAMTSL1,ADAMTSL5,ADAMTSL4,B3GNT2A,SPON1,ADAMTS5,MUC1
    O-linked glycosylation of mucins A4GNT,MUCL1,MUC4,MUC13,GALNT5,MUC5AC,GALNT6,KCNA6,B3GNT8,MUC15
    Metabolism of proteins EXOC5,IGFBP5,MPDU1B,SERPINA7,MAN1B1,PFDN1,IGFBP6A,EEF1B2,GPR116,TIMM13

    Protein Function

    MUC20 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MUC20 itself. We selected most functions MUC20 had, and list some proteins which have the same functions with MUC20. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    MUC20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC20 here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC20.

    ALDOB;ELOVL3

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