MUC13

  • Official Full Name

    mucin 13, cell surface associated
  • Overview

    Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and;glandular epithelial tissues (Williams et al., 2001 (PubMed 11278439)).
  • Synonyms

    MUC13;mucin 13, cell surface associated;down regulated in colon cancer 1 , DRCC1, mucin 13, epithelial transmembrane;mucin-13;down-regulated in colon cancer 1;mucin 13, epithelial transmembrane;DRCC1;MUC-13;FLJ20063

Recombinant Proteins

  • Mouse
  • Human
  • Mus musculus
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Fc
  • T7
  • Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
MUC13-10227M Recombinant Mouse MUC13 Protein Mammalian Cells Mouse His
MUC13-0395H Recombinant Human MUC13 protein, hFc-tagged HEK293 Human Fc Gln21-Gln420
MUC13-124H Recombinant Human MUC13 protein, His-tagged HEK293 Human His Met1-Gln420
MUC13-1506H Recombinant Human MUC13 protein, His & T7-tagged E.coli Human His&T7 Ser174~Gln404
MUC13-5802M Recombinant Mouse MUC13 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MUC13-5802M-B Recombinant Mouse MUC13 Protein Pre-coupled Magnetic Beads HEK293 Mouse
RFL16458MF Recombinant Full Length Mouse Mucin-13(Muc13) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length of Mature Protein (18-573)

    Involved Pathway

    MUC13 involved in several pathways and played different roles in them. We selected most pathways MUC13 participated on our site, such as Metabolism of proteins,O-linked glycosylation,O-linked glycosylation of mucins, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins ST6GAL2B,SLC25A12,BCS1L,CST3,PROCA,GATA6,CCT6A,ACE,ADAMTS20,YIF1A
    Termination of O-glycan biosynthesis MUC12,MUC1,MUC5AC,MUC21,MUC20,MUC15,MUCL1,MUC4
    Post-translational protein modification OTOP2,DHPS,ST6GALNAC1.2,PREB,CNIH2,ADAMTSL3,DPAGT1,NAPG,MUC20,SPON1B
    O-linked glycosylation of mucins MUC15,MUC1,MUCL1,MUC4,GALNTL5,KCNA6,GCNT3,B3GNT6,GALNT6,GALNT5
    O-linked glycosylation THSD1,GALNT5,GALNT6,ADAMTS1,SPON2,MUC5AC,B3GNT2A,MUC20,ADAMTS18,MUC15

    Protein Function

    MUC13 has several biochemical functions, for example, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MUC13 itself. We selected most functions MUC13 had, and list some proteins which have the same functions with MUC13. You can find most of the proteins on our site.

    Function Related Protein
    protein homodimerization activity CPNE1,BMP4,Pdgfa&Pdgfb,STK10,BIRC5,PRDM6,UGT1A6B,KCNK9,CSF1R,GCH1

    Interacting Protein

    MUC13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC13 here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC13.

    Resources

    References

    • Gupta, BK; Maher, DM; et al. Increased Expression and Aberrant Localization of Mucin 13 in Metastatic Colon Cancer. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 60:822-831(2012).
    • Chauhan, SC; Ebeling, MC; et al. MUC13 Mucin Augments Pancreatic Tumorigenesis. MOLECULAR CANCER THERAPEUTICS 11:24-33(2012).

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