MTUS1
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Official Full Name
microtubule associated tumor suppressor 1 -
Overview
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. -
Synonyms
MTUS1;microtubule associated tumor suppressor 1;mitochondrial tumor suppressor 1;microtubule-associated tumor suppressor 1;AT2 receptor interacting protein;AT2R binding protein;ATBP;ATIP1;DKFZp586D1519;FLJ14295;KIAA1288;mitochondrial tumor suppressor gene 1;MP44;MTSG1;Angiotensin II type 2 receptor interacting protein;ATIP;DKFZp686F20243;Erythroid differentiation related;GK 1;GK1;MP 44;MTSG 1;MTUS 1;Transcription factor MTSG1;OTTHUMP00000224769;OTTHUMP00000224771;OTTHUMP00000224772;OTTHUMP00000224773;AT2 receptor-binding protein;AT2 receptor-interacting protein;erythroid differentiation-r
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&T7
- Non
- His&Fc&Avi
- GST
Involved Pathway
MTUS1 involved in several pathways and played different roles in them. We selected most pathways MTUS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MTUS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MTUS1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MTUS1 itself. We selected most functions MTUS1 had, and list some proteins which have the same functions with MTUS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
MTUS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTUS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTUS1.
ORC4;HTT;pdaB
Resources
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References
- Boukhari, A; Alhosin, M; et al. CD47 Activation-induced UHRF1 Over-expression Is Associated with Silencing of Tumor Suppressor Gene p16(INK4A) in Glioblastoma Cells. ANTICANCER RESEARCH 35:149-157(2015).
- Hosseini, H; Rajabibazl, M; et al. Inhibiting angiogenesis with human single-chain variable fragment antibody targeting VEGF. MICROVASCULAR RESEARCH 97:13-18(2015).
