MTMR8
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Official Full Name
myotubularin related protein 8 -
Overview
This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases. -
Synonyms
MTMR8;myotubularin related protein 8;myotubularin-related protein 8;FLJ20126;FLJ60798
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MTMR8-1094H | Recombinant Human MTMR8, GST-tagged | E.coli | Human | GST | N-term-307aa | |
| MTMR8-10708Z | Recombinant Zebrafish MTMR8 | Mammalian Cell | Zebrafish | His |
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| MTMR8-1992C | Recombinant Chicken MTMR8 | Mammalian Cell | Chicken | His |
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| MTMR8-1151HCL | Recombinant Human MTMR8 cell lysate | Human | Non |
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| MTMR8-2182H | Recombinant Human MTMR8 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| MTMR8-5723H | Recombinant Human MTMR8 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MTMR8-6481H | Recombinant Human MTMR8 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| MTMR8-6546HF | Recombinant Full Length Human MTMR8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 704 amino acids |
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Involved Pathway
MTMR8 involved in several pathways and played different roles in them. We selected most pathways MTMR8 participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | PIP5K1A,PIKFYVE,NUDT4B,PIK3C3,MTMR7A,PIK3C2G,IPMK,OCRL,PLCD1B,PLCD1A |
| Metabolic pathways | HK3,AMY1A,MGAT4A,PLD3,AANAT,LDHC,G6PCA.2,MTMR4,PTGS2A,CHSY1 |
| Phosphatidylinositol signaling system | TMEM55B,ITPR1,MTMR4,INPP5D,PRKCB,PLCG2,PIK3C3,CALM1,PIK3C2A,DGKAA |
Protein Function
MTMR8 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity,phosphatidylinositol-3-phosphatase activity,protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR8 itself. We selected most functions MTMR8 had, and list some proteins which have the same functions with MTMR8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3-phosphatase activity | FIG4,SACM1L,MTMR2,MTMR1B,MTMR1,MTMR1A,PTEN,MTMR3,MTMR14,MTM1 |
| phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | CTDSPL2A,MTMR3,SACM1LB,MTMR1B,SACM1L,PTPRQ,PXYLP1,MTMR1,SGPP2,SACM1LA |
| protein tyrosine phosphatase activity | PTPN2A,PTPN14,PALD1,PTPN11,MTMR7B,DUSP21,PTPN22,PTPN20B,PTPRG,PTPRF |
Interacting Protein
MTMR8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR8.
MTMR9
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References
- Sanchez-Juan, P; Bishop, MT; et al. Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. NEUROBIOLOGY OF AGING 33:-(2012).
- Pridgeon, JW; Yeh, HY; et al. Global transcription analysis of vaccinated channel catfish following challenge with virulent Edwardsiella ictaluri. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY 146:53-61(2012).
