MTHFD1L
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Official Full Name
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -
Overview
The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is;important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine.;Several transcript variants encoding different isoforms have been found for this gene.
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MTHFD1L-1082H | Recombinant Human MTHFD1L, His-tagged | E.coli | Human | His | C-term-349 | |
| MTHFD1L-10191M | Recombinant Mouse MTHFD1L Protein | Mammalian Cells | Mouse | His |
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| MTHFD1L-8028Z | Recombinant Zebrafish MTHFD1L | Mammalian Cells | Zebrafish | His |
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| MTHFD1L-425HCL | Recombinant Human MTHFD1L lysate | HEK293 | Human | Non |
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| MTHFD1L-5703H | Recombinant Human MTHFD1L Protein, GST-tagged | Wheat Germ | Human | GST |
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| MTHFD1L-5778M | Recombinant Mouse MTHFD1L Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MTHFD1L-5778M-B | Recombinant Mouse MTHFD1L Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MTHFD1L-6528HF | Recombinant Full Length Human MTHFD1L Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 366 amino acids |
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Involved Pathway
MTHFD1L involved in several pathways and played different roles in them. We selected most pathways MTHFD1L participated on our site, such as One carbon pool by folate,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTHFD1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| One carbon pool by folate | ALDH1L1,ATIC,DHFRL1,MTHFS,AMT,MTR,TYMS,MTHFR,GART,MTHFD1B |
| Metabolic pathways | UGP2B,UGCG,ALDH1A2,ALDH9A1B,EBP,CEL.1,PLA2G4A,HPSE2,AMDHD1,MMAB |
Protein Function
MTHFD1L has several biochemical functions, for example, ATP binding,formate-tetrahydrofolate ligase activity,NOT methenyltetrahydrofolate cyclohydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTHFD1L itself. We selected most functions MTHFD1L had, and list some proteins which have the same functions with MTHFD1L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | UNC13A,CD247,DMRTC2,ZFP423,AIMP1,DROSHA,TERFA,SRF,DMRT2A,CTBP2 |
| ATP binding | CLPB,ALPK1,SPO11,ENTPD8,NLRP9C,KSR1,OASL,HSPA12B,ABCF1,ATP1A1 |
| formate-tetrahydrofolate ligase activity | MTHFD1B,MTHFD1 |
Interacting Protein
MTHFD1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTHFD1L here. Most of them are supplied by our site. Hope this information will be useful for your research of MTHFD1L.
MYC;CASP4;ILK;PSMD6;TSC22D1;USP50;NEK6;WRAP73;PHLDA3;MAGED1;ssdna_dtdc;NPM1;LRPPRC;Ncaph;MAP1LC3A;SIRT4
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