MTA2

  • Official Full Name

    metastasis associated 1 family, member 2

  • Overview

    MTA1 (metastasis associated gene 1) was identified in a differential screening of a cDNA library of metastatic and nonmetastatic adenocarcinoma cell lines (1), and was subsequently found to be an integral member of the nucleosome remodeling and deacetylat

  • Synonyms

    MTA2;metastasis associated 1 family, member 2;metastasis associated gene family, member 2 , MTA1L1;metastasis-associated protein MTA2;MTA1 L1;MTA1-L1 protein;metastasis-associated 1-like 1;metastasis-associated protein 2;metastasis -associated gen

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • GST
  • His
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
MTA2-1071H Recombinant Human MTA2, GST-tagged E.coli Human GST 1-350aa
MTA2-294H Recombinant Human MTA2 Protein, His-tagged E.coli Human His Met1~Cys394
MTA2-10162M Recombinant Mouse MTA2 Protein Mammalian Cells Mouse His
MTA2-12725Z Recombinant Zebrafish MTA2 Mammalian Cells Zebrafish His
MTA2-26H Recombinant Human MTA2 protein, GST-tagged Wheat Germ Human GST 521-620 a.a.
MTA2-2890R Recombinant Rhesus monkey MTA2 Protein, His-tagged Mammalian Cells Rhesus macaque His
MTA2-2710R Recombinant Rhesus Macaque MTA2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
MTA2-2710R-B Recombinant Rhesus Macaque MTA2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
MTA2-5298H Recombinant Human MTA2 Protein (Met1-Cys394), N-His tagged E.coli Human His Met1-Cys394
MTA2-5763M Recombinant Mouse MTA2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MTA2-5763M-B Recombinant Mouse MTA2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    MTA2 involved in several pathways and played different roles in them. We selected most pathways MTA2 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gene Expression TRMT61A,TAF1C,SMG8,HNRNPH2,C22orf28,ZNF74,EIF4H,ADAR,SMG9,POLRMT
    EGFR1 Signaling Pathway ZPR1,PTK6,JUND,GRB7,EPS8,ELF3,RGS16,DNM1,SH3BGRL,ZNF259
    RNA Polymerase I Transcription GATAD2B,GATAD2A,TAF1C,TAF1B,PTRF,PTRFB,CHD4A,MBD3A,GATAD2AB,TAF1D
    Chromatin modifying enzymes BRMS1,C20orf20,SMYD2A,SMARCA4,KAT6A,PRDM16,ACTL6B,KDM5A,JMJD6,SAP30L
    RNA Polymerase I Transcription Initiation MTA1,MBD3,GATAD2AB,MBD3B,CHD4A,GATAD2A,MTA3,MBD3A,RRN3,CHD4
    HDACs deacetylate histones SUDS3,KDM1A,GATAD2A,GATAD2B,MTA3,PHF21A,BRMS1,CHD4A,MBD3A,MBD3
    Chromatin organization C20orf20,KDM5BB,SETD3,ELP3,ING5,PHF8,ARID4A,MSL3,KIAA1267,MSL2B
    RNA Polymerase I Promoter Clearance CHD4A,CHD4,TAF1C,MTA1,MTA3,UBTF,RRN3,MBD3,EFCAB11,MBD3A

    Protein Function

    MTA2 has several biochemical functions, for example, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding,contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding,RNA polymerase II repressing transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTA2 itself. We selected most functions MTA2 had, and list some proteins which have the same functions with MTA2. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding RBBP4,SMARCC1,SMARCB1,SMARCA4,HDAC2,MBD3,HDAC1,SMARCE1,CHD4,SMARCC2
    RNA polymerase II repressing transcription factor binding DMAP1,PPARA,SP1,BBS5,HDAC2,HDAC1,BBS4,TCF7L2,RBBP8,PROL1
    contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding HDAC1,SMARCC1,SMARCB1,ACTL6A,CHD4,RBBP4,SMARCE1,SMARCA4,GATAD2B,SMARCC2
    histone deacetylase activity SIRT1,HDAC3,HDAC7,HDAC10,HDAC6,SIRT2,ATXN3L,HDAC9,NACC2,HDAC1
    contributes_to nucleosomal DNA binding HDAC1,ACTL6A,SMARCA4,GATAD2B,SMARCB1,RBBP4,MBD3,CHD4,ACTB,HDAC2
    RNA polymerase II transcription factor binding MKX,SPI1,CREBBP,GATA5,SMAD4,Ar,GATA3,ZGLP1,MTDH,ANKRD1
    transcription factor activity, transcription factor binding PER1,HIF1A,ASCL1B,NEUROG1,CRY1,LDB1A,LDB2B,ASCL1A,PER2,TP63
    protein binding SNIP1,LAPTM4B,MAP2K2,USP20,ISL1,TMEM88,CD47,TRIM10,INO80B,CUBN
    transcription factor activity, sequence-specific DNA binding DMRTA2,FOXB1B,NEUROD2,PA2G4B,CARF,ZNF544,FOXF2A,HOMEZ,RUNX3,SOX2

    Interacting Protein

    MTA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTA2.

    HDAC1;HDAC2;MBD3;PARK7

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