MSP

  • Official Full Name

    major sperm protein
  • Overview

    The major sperm protein (MSP) is a nematode specific small protein of 126 amino acids with a molecular weight of 14 kDa. It is the key player in the motility machinery of nematodes that propels the crawling movement/motility of nematode sperm. It is the most abundant protein present in nematode sperm, comprising 15% of the total protein and more than 40% of the soluble protein. MSP is exclusively synthesized in spermatocytes of the nematodes. The MSP has two main functions in the reproduction of the helminthes: i) as cytosolic component it is responsible for the crawling movement of the mature sperm (without flagellum), and ii) once released, it acts as hormone on the female germ cells, where it triggers oocyte maturation and stimulates the oviduct wall to contract to bring the oocytes into position for fertilization. MSP has first been identified in Caenorhabditis elegans.
  • Synonyms

    major sperm protein;MSP
Cat.# Product name Source (Host) Species Tag Protein Length Price
FEN1-1081p Recombinant Plasmodium vivax MSP Protein E.coli Plasmodium vivax Non
RFL32378DF Recombinant Full Length Dictyostelium Discoideum Membrane Selenoprotein(Msp) Protein, His-Tagged E.coli expression system Dictyostelium Discoideum His Full L. Full Length (1-243)

    Involved Pathway

    MSP involved in several pathways and played different roles in them. We selected most pathways MSP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MSP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    MSP has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MSP itself. We selected most functions MSP had, and list some proteins which have the same functions with MSP. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    MSP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSP here. Most of them are supplied by our site. Hope this information will be useful for your research of MSP.

    Resources

    References

    • Daou, M; Kouriba, B; et al. Protection of Malian children from clinical malaria is associated with recognition of multiple antigens. MALARIA JOURNAL 14:-(2015).
    • Espino, E; Koskenniemi, K; et al. Uncovering Surface-Exposed Antigens of Lactobacillus rhamnosus by Cell Shaving Proteomics and Two-Dimensional Immunoblotting. JOURNAL OF PROTEOME RESEARCH 14:1010-1024(2015).

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