MRPS31
-
Official Full Name
mitochondrial ribosomal protein S31 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13. -
Synonyms
MRPS31;mitochondrial ribosomal protein S31;28S ribosomal protein S31, mitochondrial;IMOGN38;Imogen 38;S31mt;MRP-S31
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
MRPS31 involved in several pathways and played different roles in them. We selected most pathways MRPS31 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation | MRPL48,MRPS34,MRPL10,PTCD3,MTFMT,ICT1,MRPL46,TUFM,MRPL44,MRPL39 |
| Mitochondrial translation termination | MRPL54,MRPS28,MRPS22,MRPL52,MRPS34,MRPL50,MRPL38,MRRF,AURKAIP1,GFM2 |
| Mitochondrial translation initiation | MRPS23,MRPL53,AURKAIP1,MTFMT,DAP3,GADD45GIP1,ICT1,MRPL10,MRPL42,MRPL49 |
| Mitochondrial translation elongation | MRPS22,MRPS33,MRPL48,MRPL42,TSFM,MRPS36,MRPL28,MRPL45,MRPL10,MRPS27 |
| Organelle biogenesis and maintenance | DYNLL2B,WDR35,MRPL48,GFM1,BBS10,TFB2M,TCTN1,DYNLL2A,PPRC1,IFT122 |
Protein Function
MRPS31 has several biochemical functions, for example, poly(A) RNA binding,protein binding,protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS31 itself. We selected most functions MRPS31 had, and list some proteins which have the same functions with MRPS31. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | RPL18A,NOP58,WIBG,SAMD4,NKAP,MAZ,SF3B4,DDX51,ZCCHC6,TFRC |
| structural constituent of ribosome | RPS26,RPS7,RPS3A,MRPS6,MRPS14,RPL36,MRPL51,RPS8B,RPS8A,RPL36AL |
| protein domain specific binding | GSN,Akap2,YWHABL,ZBTB16,HIST1H4I,RXRA,TACC2,YWHAQB,DIXDC1,KCNN2 |
| protein binding | DARS,CDCA4,NPM1,COG4,ROBO1,CLUAP1,PPIE,FOXD3,ZMYM2,SETD7 |
Interacting Protein
MRPS31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS31 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS31.
STAT3;USP42;ITGB3BP;Brwd3;ssrna_ug;MAST3;ESR1;Rab5c;YBX1;Rad54l;MEX3C;SLX4;ESR2
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