MRPS25
-
Official Full Name
mitochondrial ribosomal protein S25 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4. -
Synonyms
MRPS25;mitochondrial ribosomal protein S25;28S ribosomal protein S25, mitochondrial;DKFZp313H0817;FLJ00023;mitochondrial 28S ribosomal protein S25;MRP S25;RPMS25;28S ribosomal protein S25 mitochondrial;S25mt;OTTHUMP00000160273;OTTHUMP00000208264;OTTHUMP00000208265;OTTHUMP00000208266;OTTHUMP00000209537;MRP-S25
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
- GST
Involved Pathway
MRPS25 involved in several pathways and played different roles in them. We selected most pathways MRPS25 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS25 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation | MRPL55,MRPL10,MRPL42,CHCHD1,MRPS30,MRPL41,GFM2,MRPS27,MRPL46,MTRF1L |
| Organelle biogenesis and maintenance | BBS7,GFM2,MRPL39,NPHP4,MRPL38,MRPL40,MTRF1L,TMEM216,MRPS30,BBS13 |
| Mitochondrial translation termination | MRPL49,MRPL42,MRPL50,MRPL44,MRPL38,MRPL39,MRPL45,MRPL10,MRPL55,MRPL48 |
| Mitochondrial translation elongation | MRPL50,MRPL46,MRPS34,MRPL37,TUFM,MRPS35,MRPS33,MRPS30,MRPL39,TSFM |
| Mitochondrial translation initiation | MRPL42,MRPL3,MTFMT,MRPS30,MRPL52,MRPS23,MRPS28,MRPL44,MRPL48,MRPL37 |
Protein Function
MRPS25 has several biochemical functions, for example, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS25 itself. We selected most functions MRPS25 had, and list some proteins which have the same functions with MRPS25. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | NDUFA7,RPL5A,RPL9,RPS10,RPL39L,MRPS7,MRPL4,RPL31,RPS27.1,MRPL17 |
Interacting Protein
MRPS25 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS25 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS25.
DDX56;Brwd3;C1qbp;ZFC3H1;MME;PCNA;ERBB3;HNRNPU;ICT1;Med22;PCDHB15
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