MRPS24
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Official Full Name
mitochondrial ribosomal protein S24 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 11. Read-through transcription exists between this gene and the upstream upregulator of cell proliferation (URGCP) gene. -
Synonyms
MRPS24;mitochondrial ribosomal protein S24;28S ribosomal protein S24, mitochondrial;HSPC335;MRP S24;mitochondrial 28S ribosomal protein S24;S24mt;bMRP47;MRP-S24;bMRP-47
Recombinant Proteins
- Mouse
- Zebrafish
- Human
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MRPS24-10096M | Recombinant Mouse MRPS24 Protein | Mammalian Cells | Mouse | His |
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| MRPS24-2846Z | Recombinant Zebrafish MRPS24 | Mammalian Cells | Zebrafish | His |
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| MRPS24-4142HCL | Recombinant Human MRPS24 293 Cell Lysate | HEK293 | Human | Non |
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| MRPS24-5613H | Recombinant Human MRPS24 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MRPS24-5720M | Recombinant Mouse MRPS24 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MRPS24-5720M-B | Recombinant Mouse MRPS24 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MRPS24-6489HF | Recombinant Full Length Human MRPS24 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 167 amino acids |
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Involved Pathway
MRPS24 involved in several pathways and played different roles in them. We selected most pathways MRPS24 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation termination | MRRF,GFM2,PTCD3,MRPL48,MRPS27,MRPL52,MRPS22,MRPS34,MRPS33,DAP3 |
| Mitochondrial translation elongation | MRPS27,MRPL40,MRPL47,TSFM,MRPL53,DAP3,MRPL48,MRPL37,CHCHD1,MRPL45 |
| Mitochondrial translation | MRPL28,MRPS25,MRPL46,CHCHD1,MRPS26,MRPL3,MRPS34,GADD45GIP1,MRPL44,DAP3 |
| Mitochondrial translation initiation | DAP3,MRPL38,MRPL28,MRPL51,MRPL42,MRPL44,MRPL53,MRPS27,GADD45GIP1,MTIF3 |
| Organelle biogenesis and maintenance | TRIP11,MRPL46,RABL5,WDR19,MRPS36,ATAT1,MTRF1L,KIFAP3A,TCTN3,RP2 |
Protein Function
MRPS24 has several biochemical functions, for example, poly(A) RNA binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS24 itself. We selected most functions MRPS24 had, and list some proteins which have the same functions with MRPS24. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | HNRPLL,ZFP622,TCOF1,CSTF3,TRUB2,ARL6IP4,PURA,DIMT1L,HNRNPC,RBM12B1 |
| structural constituent of ribosome | MRPL14,MRPL9,RPL26,MRPS15,RPL13A,MRPS6,MRPL12,RPL6,RPS4Y2,MRPL15 |
Interacting Protein
MRPS24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS24 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS24.
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References
- Kocher, T; Schraml, P; et al. Identification of genes differentially expressed in melanoma sublines derived from a single surgical specimen characterised by different sensitivity to cytotoxic T-lymphocyte activity. SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT 130:617-624(2000).
- PURNELLE, B; COSTER, F; et al. THE SEQUENCE OF A 36 KB SEGMENT ON THE LEFT ARM OF YEAST CHROMOSOME-X IDENTIFIES 24 OPEN READING FRAMES INCLUDING - NUC1, PRP21 (SPP91), CDC6, CRY2, THE GENE FOR S24, A HOMOLOG TO THE ACONITASE GENE ACO1 AND 2 HOMOLOGS TO CHROMOSOME-III GENES. YEAST 10:1235-1249(1994).
