MRPS18B
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Official Full Name
mitochondrial ribosomal protein S18B -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. -
Synonyms
MRPS18B;mitochondrial ribosomal protein S18B;28S ribosomal protein S18b, mitochondrial;C6orf14;HSPC183;MRPS18 2;PTD017;mitochondrial;28S ribosomal protein S18-2;28S ribosomal protein S18b;DKFZp564H0223;HSPC 183;Mitochondrial ribosomal protein S18 2;MRP S18 2;MRP S18 b;MRP S18b;MRP-S18-2;MRP-S18-b;MRPS 18B;Mrps18-b;RT18B_HUMAN;S18amt;S18mt-b;mitochondrial ribosomal protein S18-2;28S ribosomal protein S18-2, mitochondrial;MRPS18-2;HumanS18a
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
- GST
Involved Pathway
MRPS18B involved in several pathways and played different roles in them. We selected most pathways MRPS18B participated on our site, such as Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS18B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Viral carcinogenesis | HIST1H2BB,RBPJ,UBE3A,VDAC3,HIST1H2BM,HIST1H2BP,CCND3,MAPK1,SKP2,HIST1H4I |
Protein Function
MRPS18B has several biochemical functions, for example, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS18B itself. We selected most functions MRPS18B had, and list some proteins which have the same functions with MRPS18B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | FAUA,RPS17L,RPLP1,MRPL17,RPS19,MRPS7,RPLP0,MRPL41,RPL7A,RPS3 |
Interacting Protein
MRPS18B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS18B here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS18B.
NFKBIL1;EWSR1;ssrna_ug;ERBB3;Pabpc1;Wdr5;ICT1;Prkci;ENTHD2;SIRT4
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