MRPL45
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Official Full Name
mitochondrial ribosomal protein L45 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. -
Synonyms
MRPL45;mitochondrial ribosomal protein L45;39S ribosomal protein L45, mitochondrial;MGC11321;L45mt;MRP-L45
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MRPL45-10636Z | Recombinant Zebrafish MRPL45 | Mammalian Cell | Zebrafish | His |
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| MRPL45-1096H | Recombinant Human MRPL45 | Mammalian Cell | Human | His |
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| MRPL45-4116C | Recombinant Chicken MRPL45 | Mammalian Cell | Chicken | His |
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| MRPL45-3519H | Recombinant Human MRPL45 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| MRPL45-3519H-B | Recombinant Human MRPL45 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
MRPL45 involved in several pathways and played different roles in them. We selected most pathways MRPL45 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL45 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitochondrial translation elongation | MRPL3,MRPL48,GFM1,MRPS27,DAP3,MRPL10,MRPL50,MRPL37,AURKAIP1,MRPS30 |
| Mitochondrial translation termination | MRPL37,MRPL40,MRPL53,MRPL47,MTRF1L,ICT1,MRPS30,DAP3,PTCD3,MRPL41 |
| Mitochondrial translation initiation | MRPL37,MRPS35,ICT1,MRPL49,DAP3,MRPL38,MTIF3,MRPS30,MRPL50,MRPS27 |
| Mitochondrial translation | GFM1,MRPS26,GFM2,MRPL10,AURKAIP1,MRPL28,MRPS33,GADD45GIP1,MRPS35,MRPS25 |
| Organelle biogenesis and maintenance | IFT88,IFT172,BBS4,TTC30A2,BBS13,TCTEX1D1,IFT46,TTBK2,NPHP1,GFM2 |
Protein Function
MRPL45 has several biochemical functions, for example, poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL45 itself. We selected most functions MRPL45 had, and list some proteins which have the same functions with MRPL45. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | PURB,KIAA0020,C3orf26,PA2G4,BUD13,RPS11,NSUN5,DSP,CCAR1,POLR2A |
| protein binding | URM1,SCRN2,MTTP,CDC7,APC2,SNRPD1,BPTF,SFMBT1,RPA3,STK4 |
Interacting Protein
MRPL45 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL45 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL45.
TRIM23;G3BP1;KBTBD7;C1qbp;NCAPD3;Nup188;Rpl35;MRPL50;Pip4k2c;ESR2;MRPL9;MRPL1;Dctn5
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