MRPL42

  • Official Full Name

    mitochondrial ribosomal protein L42

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a protein identified as belonging to both the 28S and the 39S subunits. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.

  • Synonyms

    MRPL42;mitochondrial ribosomal protein L42;39S ribosomal protein L42, mitochondrial;HSPC204;MRP L31;MRPL31;MRPS32;PTD007;RPML31;mitochondrial;28S ribosomal protein S32;39S ribosomal protein L31;39S ribosomal protein L42;L31mt;L42mt;Mitochondrial ribosomal protein S32;MRP L42;MRP S32;MRP-L31;MRP-L42;MRP-S32;RM42_HUMAN;S32mt;28S ribosomal protein S32, mitochondrial;39S ribosomal protein L31, mitochondrial

Recombinant Proteins

  • Mouse
  • Human
  • Mammalian Cell
  • HEK293
  • E.coli
  • HEK293T
  • His
  • Non
  • GST
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
MRPL42-10069M Recombinant Mouse MRPL42 Protein Mammalian Cell Mouse His
MRPL42-4167HCL Recombinant Human MRPL42 293 Cell Lysate HEK293 Human Non
MRPL42-3243H Recombinant Human MRPL42 protein, GST-tagged E.coli Human GST 33-142aa
MRPL42-3365H Recombinant Human MRPL42 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Mrpl42-4157M Recombinant Mouse Mrpl42 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
MRPL42-5703M Recombinant Mouse MRPL42 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
MRPL42-5703M-B Recombinant Mouse MRPL42 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    MRPL42 involved in several pathways and played different roles in them. We selected most pathways MRPL42 participated on our site, such as Mitochondrial translation,Mitochondrial translation elongation,Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitochondrial translation termination PTCD3,MRRF,MRPS24,ICT1,MRPL46,GADD45GIP1,MRPL55,GFM2,MRPL51,MRPS22
    Mitochondrial translation elongation MRPL28,MRPL45,AURKAIP1,MRPL38,MRPL55,GADD45GIP1,ICT1,DAP3,MRPS30,MRPL46
    Mitochondrial translation initiation MRPS30,MRPS35,MRPL50,MRPS22,MRPL10,MRPS31,MRPL48,MRPL44,MRPL39,CHCHD1
    Organelle biogenesis and maintenance OST4,BBS13,TRAF3IP1,MRPL53,TTC30A,IFT122,DYNLL2B,MRRF,EXOC3,MRPL55
    Mitochondrial translation MRPL51,MTRF1L,MRPS25,CHCHD1,MRPL37,MRPL41,MRPS31,AURKAIP1,MRPS30,PTCD3

    Protein Function

    MRPL42 has several biochemical functions, for example, poly(A) RNA binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL42 itself. We selected most functions MRPL42 had, and list some proteins which have the same functions with MRPL42. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding CCDC59,RCC2,FAM103A1,DHX32,PPP1R2P9,RPL14,SLC25A5,XRN1,OASL,SRP14
    structural constituent of ribosome RPS3A,MRPL55,MRPL32,FAUA,RPL35A,RPL38,MRPS5,RPL39,MRPS12,FAU

    Interacting Protein

    MRPL42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL42 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL42.

    rev;IKBKAP;EEF1A1

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