MPP2
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Official Full Name
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) -
Overview
Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs).MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions.Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. -
Synonyms
MPP2;membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2);DLG2;MAGUK p55 subfamily member 2;discs large;homolog 2;DKFZp761D0712;D11BWG0652E;Discs Large Homolog 2;DLGH2;Membrane Protein Palmitoylated 2;PALS4;discs large, homolog 2
Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His&T7
- Non
- Myc&DDK
- His
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MPP2-776H | Recombinant Human MPP2 protein, His & T7-tagged | E.coli | Human | His&T7 | Met345~Ser573 |
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| Mpp2-777M | Recombinant Mouse Mpp2 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Val3~Lys214 |
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| MPP2-4232HCL | Recombinant Human MPP2 293 Cell Lysate | HEK293 | Human | Non |
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| MPP2-3585H | Recombinant Human MPP2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Mpp2-4125M | Recombinant Mouse Mpp2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| MPP2-4596H | Recombinant Human MPP2 Protein (Met345-Ser573), N-His tagged | E.coli | Human | His | Met345-Ser573 |
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| MPP2-5509H | Recombinant Human MPP2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MPP2-6327HF | Recombinant Full Length Human MPP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 552 amino acids |
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Involved Pathway
MPP2 involved in several pathways and played different roles in them. We selected most pathways MPP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MPP2 has several biochemical functions, for example, guanylate kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MPP2 itself. We selected most functions MPP2 had, and list some proteins which have the same functions with MPP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BTG1,SLC4A4,ENTPD1,PPP2R2C,AKR1A1,ERC2,ZNF167,MAPK3,MPZL2B,CDC27 |
| guanylate kinase activity | DLG2,DLG4,MPP3,GUK1A,CARD11,CASK,TJP2,GUK1B,GUK1,DLG1 |
Interacting Protein
MPP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MPP2.
Mbp;PLK1;CSNK2B;LIN7A;GABARAP;GABARAPL2;CDC5L
Resources
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References
- Wataya-Kaneda, M; Kaneda, Y; et al. Cells derived from tuberous sclerosis show a prolonged S phase of the cell cycle and increased apoptosis. ARCHIVES OF DERMATOLOGICAL RESEARCH 293:460-469(2001).
- WESTENDORF, JM; RAO, PN; et al. CLONING OF CDNAS FOR M-PHASE PHOSPHOPROTEINS RECOGNIZED BY THE MPM2 MONOCLONAL-ANTIBODY AND DETERMINATION OF THE PHOSPHORYLATED EPITOPE. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91:714-718(1994).
