MOAP1
-
Official Full Name
modulator of apoptosis 1 -
Overview
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. -
Synonyms
MOAP1;modulator of apoptosis 1;MAP 1;paraneoplastic Ma antigen family member 4;PNMA4;MAP1;paraneoplastic antigen Ma4;paraneoplastic antigen like 4;MAP-1
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- GST
- Myc&DDK
- His&Fc&Avi
Involved Pathway
MOAP1 involved in several pathways and played different roles in them. We selected most pathways MOAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MOAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MOAP1 has several biochemical functions, for example, protein binding,ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MOAP1 itself. We selected most functions MOAP1 had, and list some proteins which have the same functions with MOAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase binding | WASH,UBOX5,CUL1B,MDM2,RAD18,SCN5A,CCDC50,NKD2,ARIH1,RPA3 |
| protein binding | DAG1,ABCB9,KIAA1530,RNF138,GFOD1,PTS,DLGAP1,HSCB,RADIL,GLTP |
Interacting Protein
MOAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MOAP1.
CAMK2D;LATS1;THOC1;PNMA5;MBIP;CACNA1A;CCDC85B;katG;lysA1;ogl
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References
- Torres, C; Linares, A; et al. The Potential Role of the Glycoprotein Osteoactivin/Glycoprotein Nonmetastatic Melanoma Protein B in Pancreatic Cancer. PANCREAS 44:302-310(2015).
- Flores, LE; Del Zotto, H; et al. Islet neogenesis-associated protein (INGAP): The role of its endogenous production as a positive modulator of insulin secretion. REGULATORY PEPTIDES 192:30-34(2014).
