MNX1

  • Official Full Name

    motor neuron and pancreas homeobox 1
  • Overview

    This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    MNX1;motor neuron and pancreas homeobox 1;motor neuron and pancreas homeobox protein 1;homeobox gene HB9;homeobox protein HB9;HB9;MNR2;Hlxb9
Cat.# Product name Source (Host) Species Tag Protein Length Price
MNX1-1967Z Recombinant Zebrafish MNX1 Mammalian Cells Zebrafish His
MNX1-6489C Recombinant Chicken MNX1 Mammalian Cells Chicken His
MNX1-4268HCL Recombinant Human MNX1 293 Cell Lysate HEK293 Human Non
Mnx1-1132M Recombinant Mouse Mnx1 Protein, MYC/DDK-tagged HEK293 Mouse Myc&DDK
MNX1-5451H Recombinant Human MNX1 Protein, GST-tagged Wheat Germ Human GST
MNX1-6289HF Recombinant Full Length Human MNX1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 401 amino acids

    Involved Pathway

    MNX1 involved in several pathways and played different roles in them. We selected most pathways MNX1 participated on our site, such as Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with MNX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Maturity onset diabetes of the young IAPP,NKX6,NEUROG3,PKLR,HHEX,BHLHA15,HES1,INS1,NEUROD1,ONECUT1

    Protein Function

    MNX1 has several biochemical functions, for example, sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MNX1 itself. We selected most functions MNX1 had, and list some proteins which have the same functions with MNX1. You can find most of the proteins on our site.

    Function Related Protein
    sequence-specific DNA binding GLI2A,CSRNP1,GLI1,SATB1A,RX1,PBX4,ZSCAN10,ZSCAN12,HOXC4,HOXB7A
    transcription factor activity, sequence-specific DNA binding GTF2H3,MAFBA,FOXE1,PBX3B,RFX5,PROX1,FOXA3,NFE2L3,TEAD3,FOXN2B

    Interacting Protein

    MNX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MNX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MNX1.

    Resources

    References

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