MNX1
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Official Full Name
motor neuron and pancreas homeobox 1 -
Overview
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MNX1;motor neuron and pancreas homeobox 1;motor neuron and pancreas homeobox protein 1;homeobox gene HB9;homeobox protein HB9;HB9;MNR2;Hlxb9
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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MNX1-1967Z | Recombinant Zebrafish MNX1 | Mammalian Cells | Zebrafish | His |
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MNX1-6489C | Recombinant Chicken MNX1 | Mammalian Cells | Chicken | His |
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MNX1-4268HCL | Recombinant Human MNX1 293 Cell Lysate | HEK293 | Human | Non |
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Mnx1-1132M | Recombinant Mouse Mnx1 Protein, MYC/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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MNX1-5451H | Recombinant Human MNX1 Protein, GST-tagged | Wheat Germ | Human | GST |
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MNX1-6289HF | Recombinant Full Length Human MNX1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 401 amino acids |
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Involved Pathway
MNX1 involved in several pathways and played different roles in them. We selected most pathways MNX1 participated on our site, such as Maturity onset diabetes of the young, which may be useful for your reference. Also, other proteins which involved in the same pathway with MNX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Maturity onset diabetes of the young | IAPP,NKX6,NEUROG3,PKLR,HHEX,BHLHA15,HES1,INS1,NEUROD1,ONECUT1 |
Protein Function
MNX1 has several biochemical functions, for example, sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MNX1 itself. We selected most functions MNX1 had, and list some proteins which have the same functions with MNX1. You can find most of the proteins on our site.
Function | Related Protein |
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sequence-specific DNA binding | GLI2A,CSRNP1,GLI1,SATB1A,RX1,PBX4,ZSCAN10,ZSCAN12,HOXC4,HOXB7A |
transcription factor activity, sequence-specific DNA binding | GTF2H3,MAFBA,FOXE1,PBX3B,RFX5,PROX1,FOXA3,NFE2L3,TEAD3,FOXN2B |
Interacting Protein
MNX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MNX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MNX1.
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