MMP28
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Official Full Name
matrix metallopeptidase 28 -
Overview
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] -
Synonyms
MMP28;matrix metallopeptidase 28;MM28;MMP25;MMP-25;MMP-28;EPILYSIN;matrix metalloproteinase-28;matrix metalloprotease MMP25
Recombinant Proteins
- Rhesus macaque
- Human
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MMP28-2793R | Recombinant Rhesus monkey MMP28 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| MMP28-449H | Recombinant Human matrix metallopeptidase 28, His-tagged | E.coli | Human | His | 123-520 a.a. |
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| MMP28-5050H | Recombinant Human MMP28, His-tagged | E.coli | Human | His |
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| MMP28-1122HCL | Recombinant Human MMP28 cell lysate | Human | Non |
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| MMP28-2614R | Recombinant Rhesus Macaque MMP28 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| MMP28-2614R-B | Recombinant Rhesus Macaque MMP28 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| MMP28-5431H | Recombinant Human MMP28 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MMP28-6278HF | Recombinant Full Length Human MMP28 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 510 amino acids |
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Involved Pathway
MMP28 involved in several pathways and played different roles in them. We selected most pathways MMP28 participated on our site, such as Matrix Metalloproteinases, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Matrix Metalloproteinases | MMP23B,MMP8,MMP11,TIMP4,BSG,MMP26,MMP17,MMP12,MMP15,MMP27 |
Protein Function
MMP28 has several biochemical functions, for example, calcium ion binding,metalloendopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP28 itself. We selected most functions MMP28 had, and list some proteins which have the same functions with MMP28. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | GM12824,MMP24,ADAM21,MMP12,MMP14B,UQCRC2B,UQCRC1,MBTPS2,ADAM10A,ADAM17 |
| calcium ion binding | RCVRNA,SNCB,ANXA3A,S100A6,GRIN1,TMEM8C,CALB2,CAPN2A,PCDH15B,EPS15 |
| zinc ion binding | ZNF257,FHL2,RNF20,BRAP,ZSWIM1,RNF148,BARD1,LMO1,ZFYVE19,ZCRB1 |
Interacting Protein
MMP28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP28 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP28.
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References
- Ramirez, J; Ruiz-Esquide, V; et al. Patients with rheumatoid arthritis in clinical remission and ultrasound-defined active synovitis exhibit higher disease activity and increased serum levels of angiogenic biomarkers. ARTHRITIS RESEARCH & THERAPY 16:-(2014).
- Gao, B; Sun, W; et al. Whole genome expression profiling and screening for differentially expressed cytokine genes in human bone marrow endothelial cells treated with humoral inhibitors in liver cirrhosis. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 32:1204-1214(2013).
