MLYCD
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Official Full Name
malonyl-CoA decarboxylase -
Overview
The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. -
Synonyms
MLYCD;malonyl-CoA decarboxylase;malonyl-CoA decarboxylase, mitochondrial;hMCD;MCD;Malonyl CoA decarboxylase;Malonyl CoA decarboxylase mitochondrial;Malonyl coenzyme A decarboxylase;MGC59795
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His&Myc&SUMO
- His&T7
- His
- Myc&DDK
- Non
- His&Myc
- His&Fc&Avi
Involved Pathway
MLYCD involved in several pathways and played different roles in them. We selected most pathways MLYCD participated on our site, such as beta-Alanine metabolism,Propanoate metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLYCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | ANI_1_2390104,DAO.1,PEX26,ACSL5,ECI2,PECR,DECR2,PEX14,EPHX2,PEX5 |
| AMPK signaling pathway | PPP2R5B,PRKAA1,PPP2R3C,CCND1,TBC1D1,PIK3CD,Scd2,IRS4,FOXO3,EIF4EBP1 |
| Propanoate metabolism | LDHB,ECHDC1,ACACB,MCEE,SUCLG1,HADHA,HADHAB,ACAT1,DLDH,BCKDHB |
| Metabolic pathways | PANK3,LSM1,DGAT2,GCDHB,ALPI,LIPT2,PPAP2B,ACSL4,NDUFS1,COX10 |
| beta-Alanine metabolism | HADHAB,ALDH1B1,ALDH9A1A.1,CNDP1,ALDH9A1B,GAD2,ALDH2.1,ALDH3A2A,GAD1,ALDH2 |
Protein Function
MLYCD has several biochemical functions, for example, malonyl-CoA decarboxylase activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLYCD itself. We selected most functions MLYCD had, and list some proteins which have the same functions with MLYCD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | CD72,HCK,INSL4,LAMA3,SCP2,TNFSF9,DPP4,DAO1,FRK,PLXNC1 |
Interacting Protein
MLYCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLYCD here. Most of them are supplied by our site. Hope this information will be useful for your research of MLYCD.
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