MKRN1

  • Official Full Name

    makorin ring finger protein 1

  • Overview

    The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of;intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the;MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000 (PubMed 10843807)).

  • Synonyms

    MKRN1;makorin ring finger protein 1;E3 ubiquitin-protein ligase makorin-1;RNF61;RING finger protein 61;FLJ21334

Recombinant Proteins

  • Human
  • Chicken
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • Flag
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
MKRN1-895H Recombinant Human MKRN1, GST-tagged E.coli Human GST N-term-349aa
MKRN1-6307C Recombinant Chicken MKRN1 Mammalian Cells Chicken His
MKRN1-9444Z Recombinant Zebrafish MKRN1 Mammalian Cells Zebrafish His
MKRN1-4300HCL Recombinant Human MKRN1 293 Cell Lysate HEK293 Human Non
MKRN1-022H Recombinant Human MKRN1 Protein, Flag-tagged HEK293 Human Flag
MKRN1-3380H Recombinant Human MKRN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Mkrn1-4085M Recombinant Mouse Mkrn1 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
MKRN1-5372H Recombinant Human MKRN1 Protein, GST-tagged Wheat Germ Human GST
MKRN1-6343HF Recombinant Full Length Human MKRN1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 482 amino acids
MKRN1-896H Recombinant Human MKRN1 protein, His-tagged E.coli Human His Lys351-Phe470

    Involved Pathway

    MKRN1 involved in several pathways and played different roles in them. We selected most pathways MKRN1 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MKRN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    presentation UBR2,RNF25,TRIM50,ERAP2,SEC23A,CYBA,TRIM41,HECTD3,RNF19B,TRIM69
    Proteasome degradation UBA5,RNF144B,DTX3L,RNF34,UBE2V1,ASB18,RNF4,VPRBP,UBE2U,ASB13
    Class I MHC mediated antigen processing &amp TRIM39,TRIM69,TPP2,ASB2,BLMH,UBE2U,GAN,HUWE1,LRR1,DTX3L
    Adaptive Immune System CD200R2,WSB1,LILRA1,CTSD,KIF4A,KLRG1,CD300A,AGO3,DZIP3,HCST
    Antigen processing: Ubiquitination &amp ASB4,RBCK1,RNF34,SPSB4,GAN,RNF6,CMTM2A,HECTD3,BLMH,UBE2V1
    Immune System CTS7,NLRP4B,WASF2,CFHL3,MGC174857,DCTN3,SIGLEC10,DDOST,AP1G1,TRIM41

    Protein Function

    MKRN1 has several biochemical functions, for example, chromatin binding,ligase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKRN1 itself. We selected most functions MKRN1 had, and list some proteins which have the same functions with MKRN1. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin-protein transferase activity PEX2,RNF43,LNX1,FBXO30B,HECTD1,RNF181,LMO7,RNF10,BRCA1,FBXO3
    protein binding RAD18,ISOC1,VPS35,CLDN8,MT3,CDC25C,AARSD1,ZNF664-FAM101A,RSPO1,MYCBP2
    poly(A) RNA binding C2orf15,SCAF4,ZFC3H1,VCP,NOL11,HNRNPL,TRMT2A,WDR36,BST2,EIF1
    ligase activity ATG10,TRIM68,PJA2,UHRF2,TRIM5,ZNRF1,MID1,MEX3C,UBE2IA,TTLL9
    zinc ion binding ABLIM1B,NR1D2B,CPA4,MIB2,UBR4,TRIM8A,FNTB,SF1,RNF25,PHF21A
    chromatin binding DMRT1,GATA2B,OVOL2,CEBPB,BARX2,BRD2,ERG,GATA2,C10orf119,BAZ1B

    Interacting Protein

    MKRN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKRN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MKRN1.

    TP53;CDKN1A;UBC;UBE2D3;ctc;X;UBE2W;EXOSC8;DUSP23

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