MFSD8
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Official Full Name
major facilitator superfamily domain containing 8 -
Overview
This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). -
Synonyms
MFSD8;major facilitator superfamily domain containing 8;ceroid lipofuscinosis, neuronal 7, late infantile, variant , CLN7;major facilitator superfamily domain-containing protein 8;MGC33302;ceroid-lipofuscinosis neuronal protein 7;ceroid-lipofuscinos
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&GST
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MFSD8-3540H | Recombinant Human MFSD8 protein, His-tagged | E.coli | Human | His | 351-421 aa | |
| MFSD8-1039H | Recombinant Human MFSD8 | Mammalian Cells | Human | His |
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| MFSD8-4111Z | Recombinant Zebrafish MFSD8 | Mammalian Cells | Zebrafish | His |
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| MFSD8-9802M | Recombinant Mouse MFSD8 Protein | Mammalian Cells | Mouse | His |
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| MFSD8-4344HCL | Recombinant Human MFSD8 293 Cell Lysate | HEK293 | Human | Non |
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| MFSD8-2165H | Recombinant Human MFSD8 Protein (1-40 aa), His-GST-tagged | E.coli | Human | His&GST | 1-40 aa |
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| MFSD8-3470H | Recombinant Human MFSD8 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| MFSD8-3470H-B | Recombinant Human MFSD8 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| MFSD8-4372H | Recombinant Human MFSD8 Protein | Wheat Germ | Human | Non |
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| MFSD8-5529M | Recombinant Mouse MFSD8 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MFSD8-5529M-B | Recombinant Mouse MFSD8 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MFSD8-6166HF | Recombinant Full Length Human MFSD8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 512 amino acids |
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| MFSD8-6204HF | Recombinant Full Length Human MFSD8 Protein | In Vitro Cell Free System | Human | Full L. 518 amino acids |
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Involved Pathway
MFSD8 involved in several pathways and played different roles in them. We selected most pathways MFSD8 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MFSD8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysosome | PSAP,PPT1,TCIRG1,CTSA,HGSNAT,DNASE2,CTSSB.2,CTSE,AP3M1,GNS |
Protein Function
MFSD8 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MFSD8 itself. We selected most functions MFSD8 had, and list some proteins which have the same functions with MFSD8. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
MFSD8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MFSD8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MFSD8.
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