MESDC2

  • Official Full Name

    mesoderm development candidate 2

  • Overview

    Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.

  • Synonyms

    MESDC2;mesoderm development candidate 2;LDLR chaperone MESD;BOCA;KIAA0081;MESD;mesoderm development protein;renal carcinoma antigen NY-REN-61

Recombinant Proteins

  • Mouse
  • Chicken
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • HEK293
  • Human Cells
  • His
  • Non
  • His&Fc&Avi
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
Mesdc2-199M Recombinant Mouse Mesdc2 protein, His-tagged E.coli Mouse His
MESDC2-2265C Recombinant Chicken MESDC2 Mammalian Cells Chicken His
MESDC2-263H Recombinant Human MESDC2 Protein, His-tagged HEK293 Human His 34-230 a.a.
MESDC2-3195H Recombinant Human Mesoderm Development Candidate 2, His-tagged Human Cells Human His 1-230 a.a.
MESDC2-3651R Recombinant Rat MESDC2 Protein Mammalian Cells Rat His
MESDC2-5169Z Recombinant Zebrafish MESDC2 Mammalian Cells Zebrafish His
MESDC2-9736M Recombinant Mouse MESDC2 Protein Mammalian Cells Mouse His
MESDC2-2398HCL Recombinant Human MESDC2 cell lysate Human Cells Human Non
MESDC2-3307R Recombinant Rat MESDC2 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
MESDC2-3307R-B Recombinant Rat MESDC2 Protein Pre-coupled Magnetic Beads HEK293 Rat
MESDC2-35H Recombinant Human MESDC2 protein, GST-tagged E.coli Human GST 1-234 aa
MESDC2-5482M Recombinant Mouse MESDC2 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
MESDC2-5482M-B Recombinant Mouse MESDC2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
MESDC2-948H Recombinant Human MESDC2 Protein, His-tagged E.coli Human His

    Involved Pathway

    MESDC2 involved in several pathways and played different roles in them. We selected most pathways MESDC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MESDC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    MESDC2 has several biochemical functions, for example, low-density lipoprotein particle receptor binding,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by MESDC2 itself. We selected most functions MESDC2 had, and list some proteins which have the same functions with MESDC2. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function GM13057,FAM19A4B,TMTC4,BCL7BA,G0S2,TEX2,DLEU7,TMEM52B,SDSL,VGLL4B
    low-density lipoprotein particle receptor binding LANCL1,LRPAP1,APOA5,PCSK9,CCDC167,APOB,AP2M1,APOE,SACS,SLC9A3R2

    Interacting Protein

    MESDC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MESDC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MESDC2.

    env;BRD4;PSMA5;ATP6V1E1;RFC3;KPNB1;SNX5;Lrp4;RAPGEF2

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