MED30

  • Official Full Name

    mediator complex subunit 30

  • Overview

    The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010]

  • Synonyms

    MED30;mediator complex subunit 30;MED30S;THRAP6;TRAP25;mediator of RNA polymerase II transcription subunit 30;TRAP/Mediator complex component TRAP25;thyroid hormone receptor associated protein 6;thyroid hormone receptor-associated protein 6;putative mediator of RNA polymerase II transcription subunit 30;thyroid hormone receptor-associated protein complex 25 kDa component

Recombinant Proteins

  • Human
  • Zebrafish
  • Rhesus macaque
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
MED30-813H Recombinant Human MED30, His-tagged E.coli Human His 1-178aa
MED30-10981Z Recombinant Zebrafish MED30 Mammalian Cells Zebrafish His
MED30-2725R Recombinant Rhesus monkey MED30 Protein, His-tagged Mammalian Cells Rhesus macaque His
MED30-4837C Recombinant Chicken MED30 Mammalian Cells Chicken His
MED30-4839C Recombinant Chicken MED30 Mammalian Cells Chicken His
MED30-66H Recombinant Human MED30 protein, His-tagged E.coli Human His 194aa(including fusion tag)
MED30-9702M Recombinant Mouse MED30 Protein Mammalian Cells Mouse His
MED30-4383HCL Recombinant Human MED30 293 Cell Lysate HEK293 Human Non
MED30-2545R Recombinant Rhesus Macaque MED30 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
MED30-2545R-B Recombinant Rhesus Macaque MED30 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Med30-4019M Recombinant Mouse Med30 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
MED30-5458M Recombinant Mouse MED30 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
MED30-5458M-B Recombinant Mouse MED30 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    MED30 involved in several pathways and played different roles in them. We selected most pathways MED30 participated on our site, such as Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Thyroid hormone signaling pathway NCOR1,MED13L,GSK3B,SIN3A,CCND1,PRKCB,PFKP,PLCD1,PIK3R1,HRAS

    Protein Function

    MED30 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity,ligand-dependent nuclear receptor transcription coactivator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED30 itself. We selected most functions MED30 had, and list some proteins which have the same functions with MED30. You can find most of the proteins on our site.

    Function Related Protein
    transcription cofactor activity CREB1,FAM48A,ZFP865,MED14,TFDP2,MSX2,SUPT20H,PSMC5,PIR,LDB1B
    RNA polymerase II transcription cofactor activity MED17,MED20,MED7,MED10,MED24,MED1,MED19,MED13,MED18,MED15
    protein binding LNPEP,G0S2,NECAB3,POLE3,CNOT6L,IGF1,SPOP,HOXA3,DCSTAMP,MORN2
    thyroid hormone receptor binding NCOR1,MED24,NCOA3,TRIP6,NR0B2,OASL,MED16,MED12,MED4,GAS2L1
    vitamin D receptor binding THRAP3,MED24,MED16,SNW1,MED4,MED14,RXRA,TAF11,MED17,TAF7
    receptor activity TRAM1,GP6,NLGN3A,ITGAX,CRLF1,GRIA4B,NLGN3B,ABP1,NLGN2A,GRIK3
    ligand-dependent nuclear receptor transcription coactivator activity MED24,CARM1,CALCOCO1,PPRC1,MED1,NCOA2,FGF2,ZCCHC12,SMARCD3,RBM14

    Interacting Protein

    MED30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED30 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED30.

    MED10;KRTAP10-9;DOCK8;CDK19;MED19;CDK8;MED9;MED26;PTBP3

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