MDFI
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Official Full Name
MyoD family inhibitor -
Overview
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. -
Synonyms
MDFI;MyoD family inhibitor;I mfa;inhibitor of MyoD family a;I MF;MDFI_HUMAN;Myogenic repressor I-mf;OTTHUMP00000016375;OTTHUMP00000016376;OTTHUMP00000196103;OTTHUMP00000196414;OTTHUMP00000196415;I-MF;I-mfa
Recombinant Proteins
- Rhesus macaque
- Mouse
- Human
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MDFI-2710R | Recombinant Rhesus monkey MDFI Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| MDFI-9658M | Recombinant Mouse MDFI Protein | Mammalian Cells | Mouse | His |
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| MDFI-2530R | Recombinant Rhesus Macaque MDFI Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| MDFI-2530R-B | Recombinant Rhesus Macaque MDFI Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| MDFI-4504H | Recombinant Human MDFI Protein, GST-tagged | Wheat Germ | Human | GST |
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| MDFI-5427M | Recombinant Mouse MDFI Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MDFI-5427M-B | Recombinant Mouse MDFI Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MDFI-6101HF | Recombinant Full Length Human MDFI Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 246 amino acids |
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Involved Pathway
MDFI involved in several pathways and played different roles in them. We selected most pathways MDFI participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MDFI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MDFI has several biochemical functions, for example, protein binding,transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MDFI itself. We selected most functions MDFI had, and list some proteins which have the same functions with MDFI. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor binding | CRY1,IFI203,HES3,SMAD2,TAF1,TRERF1,SMAD3,KAT2B,TRIB2,DAXX |
| protein binding | SOS1,IRS1,ASCL1,SRGAP1,DUSP5,DDX17,CNOT8,SMAD1,PPP1R15B,PADI4 |
Interacting Protein
MDFI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MDFI here. Most of them are supplied by our site. Hope this information will be useful for your research of MDFI.
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References
