MCU
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Official Full Name
mitochondrial calcium uniporter -
Synonyms
MCU;mitochondrial calcium uniporter;23526;ENSG00000156026;C10orf42;CCDC109A;10q22.1;FLJ46135;calcium uniporter protein, mitochondrial;calcium uniporter protein, mitochondrial;coiled-coil domain-containing protein 109A
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Mus musculus
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- GST
Involved Pathway
MCU involved in several pathways and played different roles in them. We selected most pathways MCU participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MCU were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MCU has several biochemical functions, for example, calcium channel activity,uniporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MCU itself. We selected most functions MCU had, and list some proteins which have the same functions with MCU. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium channel activity | ORAI1B,TRPC3,RYR1,CACFD1,ITPR1,PKD2L1,TRPV5,UBXN6,TRPC4B,TRPV1 |
| uniporter activity | CCDC109A |
Interacting Protein
MCU has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCU here. Most of them are supplied by our site. Hope this information will be useful for your research of MCU.
Resources
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References
- Cao, SS; Wu, MM; et al. Identification of a Putative Flavin Adenine Dinucleotide-Binding Monooxygenase as a Regulator for Myxococcus xanthus Development. JOURNAL OF BACTERIOLOGY 197:1185-1196(2015).
- Mammucari, C; Gherardi, G; et al. The Mitochondrial Calcium Uniporter Controls Skeletal Muscle Trophism In Vivo. CELL REPORTS 10:1269-1279(2015).
