MCRS1
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Official Full Name
microspherule protein 1 -
Overview
Microspherule protein 1 is a protein that in humans is encoded by the MCRS1 gene. -
Synonyms
MCRS1;microspherule protein 1;ICP22BP;INO80 complex subunit Q;INO80Q;MCRS2;MSP58;P78;INO80 complex subunit J;58 kDa microspherule protein;cell cycle-regulated factor p78;cell cycle-regulated factor (78 kDa)
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MCRS1-12466Z | Recombinant Zebrafish MCRS1 | Mammalian Cells | Zebrafish | His |
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| MCRS1-30186TH | Recombinant Human MCRS1, His-tagged | E.coli | Human | His | 14-317 a.a. |
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| MCRS1-4411HCL | Recombinant Human MCRS1 293 Cell Lysate | HEK293 | Human | Non |
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| MCRS1-4510H | Recombinant Human MCRS1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MCRS1-6089HF | Recombinant Full Length Human MCRS1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 462 amino acids |
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Involved Pathway
MCRS1 involved in several pathways and played different roles in them. We selected most pathways MCRS1 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,DNA Damage Recognition in GG-NER, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCRS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Global Genome Nucleotide Excision Repair (GG-NER) | ACTL6A,INO80E,YY1A,GPS1,PARP2,COPS5,INO80,COPS4,COPS7A,COPS8 |
| HATs acetylate histones | TADA3,ATXN7L3,TADA1,MSL2A,MSL1A,TADA2B,ING4,ING3,BRPF3,ATXN7 |
| Nucleotide Excision Repair | CCNH,RAD23AB,GTF2H4,GTF2H1,CHD1L,CUL4B,ERCC8,COPS6,USP45,NFRKB |
| DNA Repair | CETN2,EYA3,CHEK2,UIMC1,RNF4,USP43,INO80C,DCLRE1A,SMARCA5,ACTL6A |
| Chromatin modifying enzymes | ARID4A,EHMT2,USP22,KDM4A,SMARCC1B,PADI4,SMARCC2,PBRM1L,PADI2,SMARCD3 |
| Herpes simplex infection | NXF3,IL6,IFIH1,SKP2,RNASEL,SOCS3B,IL12BA,TYK2,HCFC1,LOC100033925 |
| Chromatin organization | ING5B,C20orf20,SMARCE1,ELP3,ARID2,PRMT7,SMARCA2,ELP4,SMARCD3B,MTA1 |
| DNA Damage Recognition in GG-NER | ACTL6A,COPS7A,TFPT,COPS7B,NFRKB,COPS5,INO80E,INO80B,CETN2,DDB1 |
Protein Function
MCRS1 has several biochemical functions, for example, contributes_to histone acetyltransferase activity (H4-K16 specific),contributes_to histone acetyltransferase activity (H4-K5 specific),contributes_to histone acetyltransferase activity (H4-K8 specific). Some of the functions are cooperated with other proteins, some of the functions could acted by MCRS1 itself. We selected most functions MCRS1 had, and list some proteins which have the same functions with MCRS1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to histone acetyltransferase activity (H4-K8 specific) | KANSL2,KANSL3,KIAA1267,PHF20B,KAT8,HCFC1,OGT |
| protein binding | PCM1,PPIA,NXF2,RTN4RL1,LRRFIP2,VAT1L,PDGFRA,PITPNM3,ACTN3,EHD4 |
| contributes_to histone acetyltransferase activity (H4-K16 specific) | KANSL3,PHF20B,KANSL2,KIAA1267,HCFC1,OGT,KAT8 |
| contributes_to histone acetyltransferase activity (H4-K5 specific) | PHF20B,KAT8,KANSL3,KIAA1267,KANSL2,OGT,HCFC1 |
| telomerase inhibitor activity | PINX1,POT1A,POT1 |
Interacting Protein
MCRS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCRS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCRS1.
CCDC53;DAXX;TRIM37;INO80E
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References
- Bader, AG; Schneider, ML; et al. TOJ3, a target of the v-jun transcription factor, encodes a protein with transforming activity related to human microspherule protein 1 (MCRS1). ONCOGENE 20:7524-7535(2001).
