MCM6

  • Official Full Name

    minichromosome maintenance complex component 6
  • Overview

    The MCM6 protein (minichromosome maintenance protein 6) is a nuclear 115 kD DNA-dependent ATPase. The MCM6 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM6 togethe
  • Synonyms

    MCM6;minichromosome maintenance complex component 6

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
MCM6-3398H Recombinant Human MCM6 protein, His-tagged E.coli Human His 471-821 aa
MCM6-1665C Recombinant Chicken MCM6 Mammalian Cells Chicken His
MCM6-2705R Recombinant Rhesus monkey MCM6 Protein, His-tagged Mammalian Cells Rhesus macaque His
MCM6-28042TH Recombinant Human MCM6 Wheat Germ Human Non 821 amino acids
MCM6-5241Z Recombinant Zebrafish MCM6 Mammalian Cells Zebrafish His
MCM6-9639M Recombinant Mouse MCM6 Protein Mammalian Cells Mouse His
MCM6-4416HCL Recombinant Human MCM6 293 Cell Lysate HEK293 Human Non
MCM6-2525R Recombinant Rhesus Macaque MCM6 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
MCM6-2525R-B Recombinant Rhesus Macaque MCM6 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
MCM6-2727H Recombinant Human MCM6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human Myc&DDK
MCM6-299HF Recombinant Full Length Human MCM6 Protein In Vitro Cell Free System Human Full L. 821 amino acids
Mcm6-3997M Recombinant Mouse Mcm6 Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
MCM6-4519H Recombinant Human MCM6 Protein, GST-tagged Wheat Germ Human GST
MCM6-5414M Recombinant Mouse MCM6 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
MCM6-5414M-B Recombinant Mouse MCM6 Protein Pre-coupled Magnetic Beads HEK293 Mouse
MCM6-6071HF Recombinant Full Length Human MCM6 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 821 amino acids

    Involved Pathway

    MCM6 involved in several pathways and played different roles in them. We selected most pathways MCM6 participated on our site, such as DNA replication,Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    DNA Replication POLD1,RFC4,MCM6L,PCNA,DBF4,POLD2,GMNN,POLE3,RPA2,PRIM2
    Cell cycle MAD2L1,KIF2B,MCM8,OIP5,NDEL1A,NCAPG2,GINS1,PIANP,ABL1,DYNC1I2

    Protein Function

    MCM6 has several biochemical functions, for example, ATP binding,contributes_to ATP-dependent DNA helicase activity,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM6 itself. We selected most functions MCM6 had, and list some proteins which have the same functions with MCM6. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to ATP-dependent DNA helicase activity MCM7,MCM4,NBN,MRE11A,RAD50
    single-stranded DNA binding SUB1,RPA2,ALYREF,RBMS1,HNRNPK,LRPPRC,PMS1,TDP2,BLM,TSNAX
    protein binding CNST,ECE1,FMR1,TAL1,MPZL1,AIDA,F5,EMP3,KLRG1,OLFM4
    ATP binding ABCA7,HSPA6,OXSR1A,IDH3G,UBE1Y1,IRAK4,MYO7B,DDX55,TAP1,DDX5
    identical protein binding PLK4,DDX58,LYZ,PDCD6,LCK,SIAH1A,FAS,TRP53,SERPINA1,AKT1

    Interacting Protein

    MCM6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM6.

    MCM2;MCMBP

    Resources

    References

    • Xu, YX; Fan, HY; et al. 17 beta-Estradiol enhances response of mice spleen B cells elicited by TLR9 agonist. CELLULAR IMMUNOLOGY 278:125-135(2012).
    • Calissano, C; Damle, RN; et al. Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells. MOLECULAR MEDICINE 17:1374-1382(2011).

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