MCF2L
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Official Full Name
MCF.2 cell line derived transforming sequence-like -
Overview
Guanine nucleotide exchange factor DBS is a protein that in humans is encoded by the MCF2L gene. -
Synonyms
MCF2L;MCF.2 cell line derived transforming sequence-like;guanine nucleotide exchange factor DBS;ARHGEF14;DBS;KIAA0362;OST;DBLs big sister;MCF2 transforming sequence-like protein;FLJ12122
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MCF2L-4536C | Recombinant Chicken MCF2L | Mammalian Cells | Chicken | His |
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| MCF2L-1068HCL | Recombinant Human MCF2L cell lysate | Human | Non |
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| MCF2L-301406H | Recombinant Human MCF2L protein, GST-tagged | E.coli | Human | GST | Phe328-Glu591 |
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| Mcf2l-3993M | Recombinant Mouse Mcf2l Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
MCF2L involved in several pathways and played different roles in them. We selected most pathways MCF2L participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE,G alpha (12/13) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCF2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G alpha (12/13) signalling events | ADRA1D,FGD4,GNA13,ARHGEF3,FGD4A,FGD2,DCLRE1B,NET1,ARHGEF1B,RHOAE |
| Neurotrophic factor-mediated Trk receptor signaling | RGS19,RIT2,GIPC1,DYNLT1,FAIM,RIT1 |
| Regulation of CDC42 activity | BCAR3,ARHGAP17,ARHGAP1,DOCK9,SPATA13,ITSN2,DNMBP,ARHGEF25,RALBP1,DOCK10 |
| NRAGE signals death through JNK | OBSCN,PLEKHG2,ARHGEF3,ARHGEF17,FGD4A,FGD2,ARHGAP4A,AKAP13,ARHGEF16,NET1 |
| Regulation of RhoA activity | MYO9B,AKAP13,ABR,ECT2,OBSCN,PLEKHG6,FARP1,DEF6,ARHGAP4,NET1 |
| GPCR downstream signaling | TAS2R13,INSL5,OXGR1A.2,TRPC3,DGKB,ADCYAP1B,CCL19A.2,PNOCB,CNR1,GNA13B |
| Cell death signalling via NRAGE, NRIF and NADE | ARHGEF1A,ARHGAP4A,ARHGAP4,FGD4A,ARHGEF17,ITGB3BP,AATF,CASP2,ARHGEF16,KALRNB |
| Rho GTPase cycle | ARHGAP17B,ARHGAP25,ARHGAP36,FAM13B1,ARHGAP10,ARHGAP1,ARHGAP15,CHN1,FAM13B,ARHGAP9 |
Protein Function
MCF2L has several biochemical functions, for example, 1-phosphatidylinositol binding,Rho guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MCF2L itself. We selected most functions MCF2L had, and list some proteins which have the same functions with MCF2L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-phosphatidylinositol binding | SNX9,ZFYVE1,CCDC167,FRMPD2,PICALM,SNAP91,SCIN,SNX10,WDFY3,EPB41 |
| Rho guanyl-nucleotide exchange factor activity | PLEKHG3,ARHGEF33,QUO,ARHGEF3L,VAV3B,NET1,KALRNB,ARHGEF6,SOS1,ARHGEF10L |
Interacting Protein
MCF2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCF2L here. Most of them are supplied by our site. Hope this information will be useful for your research of MCF2L.
SMAD2;AIMP2;YAE1D1;RABAC1;AGO1
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