MCAT
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Official Full Name
malonyl CoA:ACP acyltransferase (mitochondrial) -
Overview
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MCAT;malonyl CoA:ACP acyltransferase (mitochondrial);malonyl-CoA-acyl carrier protein transacylase, mitochondrial;fabD;FASN2C;MCT;MT;NET62;mitochondrial malonyltransferase;[Acyl-carrier-protein] malonyltransferase;mitochondrial malonyl CoA:ACP a
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
MCAT involved in several pathways and played different roles in them. We selected most pathways MCAT participated on our site, such as Fatty acid biosynthesis,Metabolic pathways,Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fatty Acid Biosynthesis | ACSL1A,ECHDC3,ACSL1,ACSBG1,ACACA,OLAH,ACSL5,DECR1,ACSBG2,ACSL4 |
| Fatty acid metabolism | ACADS,PTPLAD1,ACAA1,ACADSB,SCD,ACAA1A,ACSL4A,ACOX1,ACSL3B,CPT2 |
| Metabolic pathways | HPD,GAL3ST1,CYP2U1,PMVK,LIPT2,OLAH,INPP5E,CYP2P8,PYGB,SPRA |
Protein Function
MCAT has several biochemical functions, for example, [acyl-carrier-protein] S-malonyltransferase activity,poly(A) RNA binding,transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MCAT itself. We selected most functions MCAT had, and list some proteins which have the same functions with MCAT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| [acyl-carrier-protein] S-malonyltransferase activity | FASN |
| transferase activity | OXCT2B,Acnat1,HHATLA,DNMT5,GMPPAB,SULT5A1,B3GNT8,ZDHHC15A,MAPKAPK2B,UCK2B |
| poly(A) RNA binding | DDX5,C14orf93,SUB1,KCTD12,RPS15,HIST1H4L,CAST,LARP4B,UTP11L,CHTOP |
Interacting Protein
MCAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCAT here. Most of them are supplied by our site. Hope this information will be useful for your research of MCAT.
MYC;SUMO3;ICT1;Chmp3
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References
- Xu, QF; Pichichero, ME; et al. Co-colonization by Haemophilus influenzae with Streptococcus pneumoniae enhances pneumococcal-specific antibody response in young children. VACCINE 32:706-711(2014).
- Liu, KY; Kaur, R; et al. Higher Serum Levels of Interleukin 10 Occur at Onset of Acute Otitis Media Caused by Streptococcus Pneumoniae Compared to Haemophilus Influenzae and Moraxella Catarrhalis. LARYNGOSCOPE 123:1500-1505(2013).
