MBOAT1

  • Official Full Name

    membrane bound O-acyltransferase domain containing 1
  • Overview

    MBOAT1 shares structural similarity with a superfamily of membrane-bound O-acetyltransferases that transfer organic;compounds, usually fatty acids (e.g., cholesterol, diacylglycerol, palmitoyl), onto hydroxyl groups of;membrane-embedded targets (Dauwerse et al., 2007 (PubMed 17440500)).
  • Synonyms

    MBOAT1;membrane bound O-acyltransferase domain containing 1;O acyltransferase (membrane bound) domain containing 1 , OACT1;lysophospholipid acyltransferase 1;dJ434O11.1;LPEAT1;lysophosphatidylethanolamine acyltransferase 1;MGC44669;1 acylglycerophosphoethanolamine O acyltransferase;LPE acyltransferase 1;LysoPE acyltransferase;lysophospholipid acyltransferase;LysoPS acyltransferase;membrane bound O acyltransferase domain containing 1;O acyltransferase (membrane bound) domain containing 1;O acyltransferase domain containing protein 1;OACT1;LPSAT;LPLAT 1;lyso-PS acyltransferase;lysophosphatidylserine acyltransferase;1-acylglycerophosphoserine O-acyltransferase;O-acyltransferase domain-containing protein 1;O-acyltransferase (membrane bound) domain containing 1;membrane-bound O-acyltransferase domain-containing protein 1
Cat.# Product name Source (Host) Species Tag Protein Length Price
MBOAT1-1780Z Recombinant Zebrafish MBOAT1 Mammalian Cells Zebrafish His
MBOAT1-2679C Recombinant Chicken MBOAT1 Mammalian Cells Chicken His
MBOAT1-9609M Recombinant Mouse MBOAT1 Protein Mammalian Cells Mouse His
MBOAT1-5396M Recombinant Mouse MBOAT1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MBOAT1-5396M-B Recombinant Mouse MBOAT1 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    MBOAT1 involved in several pathways and played different roles in them. We selected most pathways MBOAT1 participated on our site, such as Glycerolipid metabolism,Glycerophospholipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MBOAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerolipid metabolism ALDH2,AKR1B10,MBOAT2B,AGPAT5,ALDH1B1,CEL.1,ALDH3A2A,DGAT1,PNPLA3,LYCAT
    Metabolic pathways ACSM3,ATP6V0A1,TYRP1,ALOX12E,ATP6AP1,MDH2,PCK1,CYP21A2,P4HA3,FAM213B
    Glycerophospholipid metabolism PCYT2,ADPRM,PLA2G4D,LPCAT4,PCYT1AA,PMT,AGXT2L1,ETNK1,CDS2,DGKE

    Protein Function

    MBOAT1 has several biochemical functions, for example, 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity,2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity,2-methylhexanoyl-CoA C-acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MBOAT1 itself. We selected most functions MBOAT1 had, and list some proteins which have the same functions with MBOAT1. You can find most of the proteins on our site.

    Function Related Protein
    keto acid formate lyase activity MBOAT4,MBOAT7,DGAT2L6,LPCAT3,CML2,NAT14,CML5,HHAT,ACNAT2,Acnat1
    benzoyl acetate-CoA thiolase activity LPCAT3,CML2,HHAT,MBOAT7,DGAT2L6,MBOAT4,NAT14,Acnat1,CML5,ACNAT2
    acyl-CoA N-acyltransferase activity LPCAT3,ACNAT2,NAT14,DGAT2L6,MBOAT4,CML2,Acnat1,CML5,MBOAT7,HHAT
    sterol O-acyltransferase activity ACNAT2,LPCAT3,Acnat1,HHAT,CML2,MBOAT4,CML5,DGAT2L6,MBOAT7,NAT14
    transferase activity SMYD2A,PLAUA,CDKN1BB,PDK2B,FTSJD1,INSRB,ELOVL4A,HS3ST1L2,CAMK2B1,UGT5G1
    C-acyltransferase activity Acnat1,CML5,CML2,MBOAT7,MBOAT4,NAT14,LPCAT3,DGAT2L6,ACNAT2,HHAT
    octanoyltransferase activity MBOAT7,DGAT2L6,ACNAT2,CML5,LIPT2,Acnat1,LPCAT3,CML2,HHAT,MBOAT4
    N-acyltransferase activity NAT14,HHAT,ACNAT2,HRASLS5,CML5,CML2,LPCAT3,MBOAT7,DGAT2L6,MBOAT4
    lanosterol O-acyltransferase activity NAT14,MBOAT7,HHAT,ACNAT2,LPCAT3,CML2,MBOAT4,Acnat1,DGAT2L6,CML5

    Interacting Protein

    MBOAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MBOAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MBOAT1.

    Resources

    References

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