MAU2

  • Official Full Name

    MAU2 sister chromatid cohesion factor

  • Overview

    Scc4 (Mau2) is the metazoan homologue of Scc4 in S. cerevisiae. In yeast, Scc4 binds to Scc2 to form an essential complex that loads cohesion onto chromosomes. Similarly, the Scc4 / Mau2 protein in metazoans plays a significant role in sister chromatid separation and in loading of cohesin onto chromatin. The Scc2-Scc4 complex is tethered to pre-replication complexes through the Cdc7-Drf1 protein kinase DDK.

  • Synonyms

    MAU2;MAU2 sister chromatid cohesion factor;SCC4;MAU2L;mau-2;KIAA0892;MAU2 chromatid cohesion factor homolog;protein MAU-2;sister chromatid cohesion 4;cohesin loading complex subunit SCC4 homolog
Cat.# Product name Source (Host) Species Tag Protein Length Price
MAU2-9592M Recombinant Mouse MAU2 Protein Mammalian Cells Mouse His
MAU2-910HCL Recombinant Human MAU2 cell lysate Human Non
MAU2-5390M Recombinant Mouse MAU2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MAU2-5390M-B Recombinant Mouse MAU2 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    MAU2 involved in several pathways and played different roles in them. We selected most pathways MAU2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAU2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cohesin Loading onto Chromatin NIPBLA,PDS5A,WAPAL,NIPBL,STAG2,STAG1,PDS5B,NIPBLB
    Mitotic Telophase/Cytokinesis NIPBLB,NIPBL,NIPBLA,NUDC
    Cell Cycle, Mitotic SGOL1,LIN37,GORASP2,BLZF1,CCDC99,DCTN1,GORASP1,CENPH,GMNN,ENSA
    Cell cycle SMAD3B,CEP164,GINS2,ARPP19B,DYNC1I2,TOP2A,YWHAE1,ANAPC4,CDK7,ORC4
    M Phase NSL1,GORASP2,CENPP,LEMD3,GOLGA2,SMC2,SETA,NUDC,NCAPG,CENPK

    Protein Function

    MAU2 has several biochemical functions, for example, protein N-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAU2 itself. We selected most functions MAU2 had, and list some proteins which have the same functions with MAU2. You can find most of the proteins on our site.

    Function Related Protein
    protein N-terminus binding SCT,RASSF1,TAF11,ZWINT,SCFD1,NBN,KCNIP1,SMARCC1,PHB2,SYNGR3
    protein binding PRSS3,TCF12,LRPPRC,RBM39,CAMP,ACVR1B,PDCL3,FAM59A,DCX,MINK1

    Interacting Protein

    MAU2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAU2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAU2.

    CBX5;C21orf59;CBX1;Myh10;NIPBL;SRCAP;DNAJC7

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